ArticlePloS one2013
Influence of vectors' risk-spreading strategies and environmental stochasticity on the epidemiology and evolution of vector-borne diseases: the example of Chagas' disease.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Increased mortality attributed to Chagas disease: a systematic review and meta-analysis.Parasites & vectors · 2016Pooled it
- Seasonal variations of Triatoma dimidiata demography and Trypanosoma cruzi transmission within its multi-host community in the Yucatan Peninsula, Mexico: Insights from an integrative SIR eco-epidemiological modelling.PLoS neglected tropical diseases · 2026Article
- Sensitivity analysis of factors influencing the ecology of mosquitoes involved in the transmission of Rift Valley fever virus.PLoS neglected tropical diseases · 2026Article
- Nonlinear effects of noise on outbreaks of mosquito-borne diseases.PLoS computational biology · 2026Article
- A compartment and metapopulation model of Rocky Mountain spotted fever in southwestern United States and northern Mexico.Infectious Disease Modelling · 2024Article
- The epidemiology of Chagas disease in the Americas.Lancet regional health. Americas · 2024Review
- NaturalInsects · 2023Article
- Trypanosoma cruzi transmission dynamics in a synanthropic and domesticated host community.PLoS neglected tropical diseases · 2019Article
- Dynamics of two pathogens in a single tick population.Letters in biomathematics · 2019Article
- Environmental limits of Rift Valley fever revealed using ecoepidemiological mechanistic models.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Evolutionary ecology of Chagas disease; what do we know and what do we need?Evolutionary applications · 2018Review
- A global perspective on hepatitis B-related single nucleotide polymorphisms and evolution during human migration.Hepatology communications · 2017Article
- Impact of life stage-dependent dispersal on the colonization dynamics of host patches by ticks and tick-borne infectious agents.Parasites & vectors · 2017Article
- Intrusive versus domiciliated triatomines and the challenge of adapting vector control practices against Chagas disease.Memorias do Instituto Oswaldo Cruz · 2015Article
- Biological Control of the Chagas Disease Vector Triatoma infestans with the Entomopathogenic Fungus Beauveria bassiana Combined with an Aggregation Cue: Field, Laboratory and Mathematical Modeling Assessment.PLoS neglected tropical diseases · 2015Article
- Article
- A spatially explicit metapopulation model and cattle trade analysis suggests key determinants for the recurrent circulation of rift valley Fever virus in a pilot area of madagascar highlands.PLoS neglected tropical diseases · 2014Article
- Competition, virulence, host body mass and the diversification of macro-parasites.Journal of the Royal Society, Interface · 2014Article
- The improbable transmission of Trypanosoma cruzi to human: the missing link in the dynamics and control of Chagas disease.PLoS neglected tropical diseases · 2013Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Insects are known to display strategies that spread the risk of encountering unfavorable conditions, thereby decreasing the extinction probability of genetic lineages in unpredictable environments. To what extent these strategies influence the epidemiology and evolution of vector-borne diseases in stochastic environments is largely unknown. In triatomines, the vectors of the parasite Trypanosoma cruzi, the etiological agent of Chagas' disease, juvenile development time varies between individuals and such variation most likely decreases the extinction risk of vector populations in stochastic environments. We developed a simplified multi-stage vector-borne SI epidemiological model to investigate how vector risk-spreading strategies and environmental stochasticity influence the prevalence and evolution of a parasite. This model is based on available knowledge on triatomine biodemography, but its conceptual outcomes apply, to a certain extent, to other vector-borne diseases. Model comparisons between deterministic and stochastic settings led to the conclusion that environmental stochasticity, vector risk-spreading strategies (in particular an increase in the length and variability of development time) and their interaction have drastic consequences on vector population dynamics, disease prevalence, and the relative short-term evolution of parasite virulence. Our work shows that stochastic environments and associated risk-spreading strategies can increase the prevalence of vector-borne diseases and favor the invasion of more virulent parasite strains on relatively short evolutionary timescales. This study raises new questions and challenges in a context of increasingly unpredictable environmental variations as a result of global climate change and human interventions such as habitat destruction or vector control.
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