ArticlePloS one2013
An S-type anion channel SLAC1 is involved in cryptogein-induced ion fluxes and modulates hypersensitive responses in tobacco BY-2 cells.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 33 citations in OpenAlex.
- Plant Immunity-Activating Endophytic Bacteria Induce Dynamic Metabolic Changes in Cultured Plant Cells Without Inhibiting Their Growth.Microbial biotechnology · 2026Article
- Abscisic acid regulates ClHorticulture research · 2024Article
- Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model.Nature communications · 2023Article
- Cassava (Frontiers in plant science · 2022Article
- Ozone Induced Stomatal Regulations, MAPK and Phytohormone Signaling in Plants.International journal of molecular sciences · 2021Review
- Identification and Expression Analysis ofInternational journal of molecular sciences · 2021Article
- The Importance of ClFrontiers in plant science · 2019Review
- Arabidopsis GCN2 kinase contributes to ABA homeostasis and stomatal immunity.Communications biology · 2019Article
- Involvement of S-type anion channels in disease resistance against an oomycete pathogen in Arabidopsis seedlings.Communicative & integrative biology · 2018Article
- Autophagy, programmed cell death and reactive oxygen species in sexual reproduction in plants.Journal of plant research · 2017Review
- Stomatal Closure and Rise in ROS/NO of Arabidopsis Guard Cells by Tobacco Microbial Elicitors: Cryptogein and Harpin.Frontiers in plant science · 2017Article
- Glutamate functions in stomatal closure in Arabidopsis and fava bean.Journal of plant research · 2016Article
- Guard cell SLAC1-type anion channels mediate flagellin-induced stomatal closure.The New phytologist · 2015Article
- New approaches to the biology of stomatal guard cells.Plant & cell physiology · 2014Review
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pharmacological evidence suggests that anion channel-mediated plasma membrane anion effluxes are crucial in early defense signaling to induce immune responses and hypersensitive cell death in plants. However, their molecular bases and regulation remain largely unknown. We overexpressed Arabidopsis SLAC1, an S-type anion channel involved in stomatal closure, in cultured tobacco BY-2 cells and analyzed the effect on cryptogein-induced defense responses including fluxes of Cl(-) and other ions, production of reactive oxygen species (ROS), gene expression and hypersensitive responses. The SLAC1-GFP fusion protein was localized at the plasma membrane in BY-2 cells. Overexpression of SLAC1 enhanced cryptogein-induced Cl(-) efflux and extracellular alkalinization as well as rapid/transient and slow/prolonged phases of NADPH oxidase-mediated ROS production, which was suppressed by an anion channel inhibitor, DIDS. The overexpressor also showed enhanced sensitivity to cryptogein to induce downstream immune responses, including the induction of defense marker genes and the hypersensitive cell death. These results suggest that SLAC1 expressed in BY-2 cells mediates cryptogein-induced plasma membrane Cl(-) efflux to positively modulate the elicitor-triggered activation of other ion fluxes, ROS as well as a wide range of defense signaling pathways. These findings shed light on the possible involvement of the SLAC/SLAH family anion channels in cryptogein signaling to trigger the plasma membrane ion channel cascade in the plant defense signal transduction network.
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