ArticleClinical epidemiology2013
Rotavirus gastroenteritis in children under 5 years in the Kingdom of Bahrain: hospital-based surveillance.
Article in Clinical epidemiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Systematic review of the rotavirus infection burden in the WHO-EMRO region.Human vaccines & immunotherapeutics · 2019Pooled it
- Gastrointestinal Panel Performance for the Diagnosis of Acute Gastroenteritis in Pediatric Patients.Cureus · 2024Article
- Rotavirus Prevalence in Children with Acute Gastroenteritis Admitted to a Tertiary Hospital in Somalia in 2020-2023: A Retrospective, Single-Center Study.Pediatric health, medicine and therapeutics · 2024Article
- Molecular Epidemiology and Surveillance of Human Adenovirus and Rotavirus A Associated Gastroenteritis in Riyadh, Saudi Arabia.Tropical medicine and infectious disease · 2023Article
- Epidemiological, molecular, and clinical features of rotavirus infections among pediatrics in Qatar.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021Article
- Circulating rotavirus G and P strains post rotavirus vaccination in Eastern Mediterranean Region.Saudi medical journal · 2018Review
- Foodborne disease and food control in the Gulf States.Food control · 2017Review
- Gastroenteritis attributable to rotavirus in hospitalized Saudi Arabian children in the period 2007-2008.Clinical epidemiology · 2015Article
- Review of global rotavirus strain prevalence data from six years post vaccine licensure surveillance: is there evidence of strain selection from vaccine pressure?Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2014Review
- The role of rotavirus associated with pediatric gastroenteritis in a general hospital in Lagos, Nigeria.Germs · 2013Article
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Authors and funding
5 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeRotavirus (RV) is the leading cause of morbidity and mortality in children under 5 years of age worldwide. This study assessed the role of RV as a cause of gastroenteritis (GE)-associated hospitalization in children, generating baseline information to evaluate the potential impact of the RV vaccine in reducing RVGE disease burden in the Kingdom of Bahrain.
methodsThis single, pediatric hospital-based surveillance study was conducted over a period of 12 months beginning April 1, 2006. A total of 314 children aged under 5 years and hospitalized due to GE were enrolled in the study, following collection of written informed consent from parents/guardians. Stool samples were tested for the presence of RV using enzyme immunoassay, and a random subset of RV-positive samples was further genotyped using reverse transcriptase-polymerase chain reaction and reverse hybridization assay.
resultsOf 314 enrolled children, 239 were included in the final analysis. RV was detected in 107 children (44.8%), mostly in the 6-23 months age group (82/107; 76.6%). RVGE occurred throughout the year, with the highest proportion occurring during April (26/42; 61.9%). G1P[8[ was the most commonly detected RV strain (10/17; 58.8%) in the limited number of samples analyzed. Vomiting and severe RVGE were more commonly observed in RV-positive than RV-negative children before hospitalization (P = 0.0008 and 0.0204, respectively).
conclusionIn our study, RV accounted for over 40% of GE-associated hospitalizations and particularly affected children under 2 years of age. These data will serve as a baseline for assessing the potential changes in the epidemiology of RV disease and for evaluating the potential impact of the introduction of RV vaccination.
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