ArticleJournal of the American Psychiatric Nurses Association
In search of an adult attachment stress provocation to measure effect on the oxytocin system: a pilot validation study.
Article in Journal of the American Psychiatric Nurses Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Pedunculopontine-induced cortical decoupling as the neurophysiological locus of dissociation.Psychological review · 2023Article
- Oxytocin receptor gene, post-traumatic stress disorder and dissociation in a community sample of European American women.BJPsych open · 2022Article
- Relation of Promoter Methylation of the Oxytocin Gene to Stressful Life Events and Depression Severity.Journal of molecular neuroscience : MN · 2020Article
- Peripheral oxytocin is inversely correlated with cognitive, but not emotional empathy in schizophrenia.PloS one · 2020Article
- Exploring the mutual regulation between oxytocin and cortisol as a marker of resilience.Archives of psychiatric nursing · 2019Article
- Endogenous oxytocin response to film scenes of attachment and loss is pronounced in schizophrenia.Social cognitive and affective neuroscience · 2019Article
- The Associations Between Oxytocin and Trauma in Humans: A Systematic Review.Frontiers in pharmacology · 2018Review
- Lower Oxytocin Plasma Levels in Borderline Patients with Unresolved Attachment Representations.Frontiers in human neuroscience · 2016Article
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Authors and funding
6 authors.
Funding
Abstract
backgroundOxytocin is a promising biomarker for psychiatric conditions arising from early relational trauma, childhood maltreatment, and attachment dysregulation, including posttraumatic stress and dissociative disorders.
objectiveThis exploratory pilot study examined plasma oxytocin as a biomarker for alterations in the attachment system.
designWe used a single group, repeated-measures design with 15 women. The protocol used a film clip previously validated as a provocation to the hypothalamic-pituitary-adrenal axis.
resultsThe repeated-measures ANOVA showed differences in oxytocin across the three time points. Correlations with oxytocin indicated that measures of dissociation and somatization correlated most strongly with higher levels of oxytocin measured during exposure to the film's bonding scene and posttraumatic stress disorder correlated most strongly with lower levels at the film's abandonment scene. Post hoc analyses revealed differences in oxytocin response related to psychopathology.
conclusionReplication studies should characterize participants on a range of psychiatric conditions associated with attachment dysregulation.
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Registered trials
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