SynthesisChest2013
Interventions to improve the physical function of ICU survivors: a systematic review.
Synthesis in Chest, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06551636 (Effects on the Expiratoriy Flow of Assisted Autogen Drainage in a Critical Patient Wtih Invasive Mechanical Ventilation), which is not on this map. Cited by 55 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects on the Expiratoriy Flow of Assisted Autogen Drainage in a Critical Patient Wtih Invasive Mechanical Ventilation
Who cites it
55 citing papers in PubMed, 5 syntheses or guidelines pooled it, 146 citations in OpenAlex.
- Effect of neuromuscular electrical stimulation in critically ill adults with mechanical ventilation: a systematic review and network meta-analysis.BMC pulmonary medicine · 2024Pooled it
- Early mobilization of critically ill patients in the intensive care unit: A systematic review and meta-analysis.PloS one · 2019Pooled it
- Exercise rehabilitation following intensive care unit discharge for recovery from critical illness: executive summary of a Cochrane Collaboration systematic review.Journal of cachexia, sarcopenia and muscle · 2016Pooled it
- Exercise rehabilitation following intensive care unit discharge for recovery from critical illness.The Cochrane database of systematic reviews · 2015Pooled it
- Effect of Early Rehabilitation during Intensive Care Unit Stay on Functional Status: Systematic Review and Meta-Analysis.PloS one · 2015Pooled it
- Feasibility of establishing a rehabilitation programme in a Vietnamese intensive care unit.PloS one · 2021Trial
- Effects of Early Exercise Rehabilitation on Functional Recovery in Patients with Severe Sepsis.Yonsei medical journal · 2018Trial
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- Trial
- TryCYCLE: A Prospective Study of the Safety and Feasibility of Early In-Bed Cycling in Mechanically Ventilated Patients.PloS one · 2016Trial
- Trial
- Early physical rehabilitation in intensive care patients with sepsis syndromes: a pilot randomised controlled trial.Intensive care medicine · 2015Trial
- Article
- Interventions for adult survivors discharged from the intensive care unit: a scoping review.BMJ open · 2025Article
- Article
- Relationship of Age And Mobility Levels During Physical Rehabilitation With Clinical Outcomes in Critical Illness.Archives of rehabilitation research and clinical translation · 2023Article
- Article
- Article
- Article
- Active Rehabilitation in a Patient During and After Venovenous Extracorporeal Membrane Oxygenation With a Diagnosis of COVID-19: A Case Report.Journal of acute care physical therapy · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundICU admissions are ever increasing across the United States. Following critical illness, physical functioning (PF) may be impaired for up to 5 years. We performed a systematic review of randomized controlled trials evaluating the efficacy of interventions targeting PF among ICU survivors. The objective of this study was to identify effective interventions that improve long-term PF in ICU survivors.
methodsMEDLINE, Excerpta Medica Database (EMBASE), Cumulative Index to Nursing and Allied Health Literature (CINAHL), and Physiotherapy Evidence-Based Database (PEDro) were searched between 1990 and 2012. Two reviewers independently evaluated studies for eligibility, critically appraised the included studies, and extracted data into standardized evidence tables.
resultsFourteen studies met the inclusion criteria. Interventions included exercise/physical therapy (PT), parenteral nutrition, nurse-led follow-up, spontaneous awakening trials, absence of sedation during mechanical ventilation, and early tracheotomy. Nine studies failed to demonstrate efficacy on PF of the ICU survivors. However, early physical exercise and PT-based interventions had a positive effect on long-term PF.
conclusionsThe only effective intervention to improve long-term PF in critically ill patients is exercise/PT; its benefit may be greater if started earlier. Further research in this area comparing different interventions and timing is needed.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.