Evidence map›Paper›PMID 23948166›Full record

ArticleBiomaterials2013

Accelerated fatigue of dentin with exposure to lactic acid.

D Do, S Orrego, H Majd, H Ryou, M M Mutluay, Hockin H K Xu, D Arola

Open access · greenAbstract read
In one paragraph

Article in Biomaterials, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Effect ofDental research journal · 2021
    Article
  3. Article
  4. Calibration of a lactic-acid model for simulating biofilm-induced degradation of the dentin-composite interface.Dental materials : official publication of the Academy of Dental Materials · 2017
    Article
  5. The Tooth: Its Structure and Properties.Dental clinics of North America · 2017
    Review
  6. Fatigue testing of biomaterials and their interfaces.Dental materials : official publication of the Academy of Dental Materials · 2017
    Article
  7. Degradation in the fatigue crack growth resistance of human dentin by lactic acid.Materials science & engineering. C, Materials for biological applications · 2017
    Article
  8. Article
  9. Degradation in the fatigue strength of dentin by diamond bur preparations: Importance of cutting direction.Journal of biomedical materials research. Part B, Applied biomaterials · 2016
    Article
  10. On the durability of resin-dentin bonds: Identifying the weakest links.Dental materials : official publication of the Academy of Dental Materials · 2015
    Article
  11. Fatigue failure of dentin-composite disks subjected to cyclic diametral compression.Dental materials : official publication of the Academy of Dental Materials · 2015
    Article
  12. Synergistic degradation of dentin by cyclic stress and buffer agitation.Journal of the mechanical behavior of biomedical materials · 2015
    Article
  13. Degradation in the fatigue strength of dentin by cutting, etching and adhesive bonding.Dental materials : official publication of the Academy of Dental Materials · 2014
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

D Do *Department of Mechanical Engineering, University of Maryland Baltimore County, Baltimore, MD USA.
S Orrego *Department of Mechanical Engineering, University of Maryland Baltimore County, Baltimore, MD USA.
H MajdDepartment of Mechanical Engineering, University of Maryland Baltimore County, Baltimore, MD USA.
H RyouDepartment of Mechanical Engineering, University of Maryland Baltimore County, Baltimore, MD USA.
M M MutluayDepartment of Mechanical Engineering, University of Maryland Baltimore County, Baltimore, MD USA.
Hockin H K XuDepartment of Endodontics, Prosthodontics, and Operative Dentistry, Dental School, University of Maryland, Baltimore, MD 21201.
D ArolaDepartment of Mechanical Engineering, University of Maryland Baltimore County, Baltimore, MD USA.
University of Maryland, Baltimore County · USUniversity of Maryland, Baltimore · USUniversity of Turku · FI

Funding

Development of high performance, caries-inhibiting dental nano-materialsR01DE017974 · NIDCR · UNIVERSITY OF MARYLAND BALTIMORE · PI XU, HUAKUN · 2008 to 2011
$1.0M
Aging and Fatigue Crack Growth in DentinR01DE016904 · NIDCR · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI AROLA, DWAYNE DALE · 2007 to 2010
$1.0M
NIDCR NIH HHS R01 DE016904NIDCR NIH HHS R01 DE017974
6 · The paper itself

Abstract

Composite restorations accumulate more biofilm than other dental materials. This increases the likelihood for the hard tissues supporting a restoration (i.e. dentin and enamel) to be exposed to acidic conditions beyond that resulting from dietary variations. In this investigation the fatigue strength and fatigue crack growth resistance of human coronal dentin were characterized within a lactic acid solution (with pH = 5) and compared to that of controls evaluated in neutral conditions (pH = 7). A comparison of the fatigue life distributions showed that the lactic acid exposure resulted in a significant reduction in the fatigue strength (p ≤ 0.001), and nearly 30% reduction in the apparent endurance limit (from 44 MPa to 32 MPa). The reduction in pH also caused a significant decrease (p ≤ 0.05) in the threshold stress intensity range required for the initiation of cyclic crack growth, and significant increase in the incremental rate of crack extension. Exposure of tooth structure to lactic acid may cause demineralization, but it also increases the likelihood of restored tooth failures via fatigue, and after short time periods.

Indexed as

AdolescentAdultDental EnamelDentinHumansHydrogen-Ion ConcentrationLactic AcidMicroscopy, Electron, ScanningStress, MechanicalSurface PropertiesTooth DemineralizationYoung AdultLactic AcidCyclic crack growthDemineralizationDentin tubulesFatigueFracture toughness

Identifiers

PMID23948166
PMCPMC3772674
OpenAlexW2054337754

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.