Evidence map›Paper›PMID 23947613›Full record

ReviewRetrovirology2013

SIV infection of rhesus macaques of Chinese origin: a suitable model for HIV infection in humans.

Yu Zhou, Rong Bao, Nancy L Haigwood, Yuri Persidsky, Wen-zhe Ho

Open access · goldAbstract readReview
In one paragraph

Review in Retrovirology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
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  7. Intra-hostMicrobiology spectrum · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Yu ZhouThe Center for Animal Experiment/ ABSL-III Laboratory, State Key Laboratory of Virology, Wuhan University School of Medicine, Wuhan, Hubei 430071, P,R, China.
Rong Bao
Nancy L Haigwood
Yuri Persidsky
Wen-zhe Ho
Temple University · USWuhan University · CNOregon National Primate Research Center · US

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
Drug Abuse, Sustance P and HIVR01DA012815 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI HO, WENZHE · 2000 to 2013
$4.5M
Opioids, HIV/HCV and Host Cell Innate ImmunityR01DA022177 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI HO, WENZHE · 2007 to 2017
$2.9M
Opioids, LPS and HIVR01DA027550 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI HO, WENZHE · 2010 to 2014
$1.4M
Opioid, Astroglial TLR3/RIG-I Signaling and HIVR21DA036163 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI HO, WENZHE · 2013 to 2014
$426k
NIDA NIH HHS DA012815NIDA NIH HHS DA022177NIDA NIH HHS DA027550NIDA NIH HHS R01 DA012815NIDA NIH HHS R01 DA027550NIDA NIH HHS R21 DA036163NIH HHS OD011092
6 · The paper itself

Abstract

Simian immunodeficiency virus (SIV) infection of Indian-origin rhesus macaques (RM) has been widely used as a well-established nonhuman primate (NHP) model for HIV/AIDS research. However, there have been a growing number of studies using Chinese RM to evaluate immunopathogenesis of SIV infection. In this paper, we have for the first time reviewed and discussed the major publications related to SIV or SHIV infection of Chinese RM in the past decades. We have compared the differences in the pathogenesis of SIV infection between Chinese RM and Indian RM with regard to viral infection, immunological response, and host genetic background. Given AIDS is a disease that affects humans of diverse origins, it is of importance to study animals with different geographical background. Therefore, to examine and compare results obtained from RM models of Indian and Chinese origins should lead to further validation and improvement of these animal models for HIV/AIDS research.

Indexed as

Macaca mulattaAnimalsDisease Models, AnimalHIVHumansSimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency Virus

Identifiers

PMID23947613
PMCPMC3765527
OpenAlexW2104100656

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.