ArticleThe Journal of asthma : official journal of the Association for the Care of Asthma2013
Asthma and severity of 2009 novel H1N1 influenza: a population-based case-control study.
Article in The Journal of asthma : official journal of the Association for the Care of Asthma, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Risk factors for serious outcomes associated with influenza illness in high- versus low- and middle-income countries: Systematic literature review and meta-analysis.Influenza and other respiratory viruses · 2018Pooled it
- Artificial intelligence biomarker detects high-risk childhood asthma subgroup for respiratory infections and exacerbations.The Journal of allergy and clinical immunology · 2025Article
- Pregnancy enhances antiviral immunity independent of type I IFN but dependent on IL-17-producing γδScience advances · 2024Article
- COVID-19, Obstructive Airway Disease and Eosinophils: A complex interplay.Sultan Qaboos University medical journal · 2022Article
- Human Rhinovirus Infection Enhances the Th2 Environment in Allergic and Non-allergic Patients with Chronic Rhinosinusitis.Clinical and experimental otorhinolaryngology · 2021Article
- Beyond Respiratory Syncytial Virus and Rhinovirus in the Pathogenesis and Exacerbation of Asthma: The Role of Metapneumovirus, Bocavirus and Influenza Virus.Immunology and allergy clinics of North America · 2019Review
- Influenza in Asthmatics: For Better or for Worse?Frontiers in immunology · 2018Review
- SELECTED EPIDEMICS & EMERGING PATHOGENS - RESPIRATORY ILLNESSES - AN OVERVIEW.Disease-a-month : DM · 2017Review
- Asthma and the Risk of Rheumatoid Arthritis: An Insight into the Heterogeneity and Phenotypes of Asthma.Tuberculosis and respiratory diseases · 2017Review
- Vaccinology in the third millennium: scientific and social challenges.Current opinion in virology · 2016Review
- Risks for infection in patients with asthma (or other atopic conditions): is asthma more than a chronic airway disease?The Journal of allergy and clinical immunology · 2014Review
- Global infectious diseases - the new norm for the United States?Disease-a-month : DM · 2013Article
- Risk of herpes zoster in children with asthma.Allergy and asthma proceedingsArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
Abstract
backgroundAsthma has been shown to be associated with an increased risk of the 2009 novel H1N1 influenza (H1N1) infection among children. However, little is known about the role of asthma in severity of H1N1 infection.
objectiveTo determine the association between asthma and other atopic conditions and severity of H1N1 infection. PATIENTS AND
methodsWe conducted a population-based case-control study. Cases were all Olmsted County, MN residents admitted to the hospital within a week of a positive test for H1N1. Controls who had a positive H1N1 but were not admitted to hospital were individually matched to cases with regard to birth day, gender, clinic registration date, diagnostic method, and calendar month of influenza testing. Asthma was ascertained using predetermined criteria. Data were fit to conditional logistic regression models.
resultsThere were 46 eligible individuals admitted to hospitals with H1N1 infection during the study period. Ninety-seven controls were individually matched to their corresponding cases. Among cases, 23 (50%) were male and 29 (63.0%) were Caucasians. The median age at hospitalization was 20.7 years. Twenty-five (54.4%) cases had asthma before the date of hospitalization, compared to 33 (34.0%) controls (matched OR: 2.31; 95% CI, 1.13-4.73; p = 0.02). This association approached statistical significance after adjusting for all pertinent covariates (adjusted matched OR: 2.55; 95% CI, 0.98-6.64; p = 0.055).
conclusionAsthma may be associated with severe H1N1 infection. In addition to timely influenza vaccination for asthmatics, consideration for prophylactic treatment for unimmunized asthmatics with significant exposure to influenza and immunized asthmatics with early flu-like symptoms should be given.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.