Evidence map›Paper›PMID 23947358›Full record

ReviewImmunological reviews2013

Dual role of commensal bacteria in viral infections.

Jessica Wilks, Helen Beilinson, Tatyana V Golovkina

Abstract readReview
In one paragraph

Review in Immunological reviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 54 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jessica WilksDepartment of Microbiology, University of Chicago, Chicago, IL 60637, USA.
Helen Beilinson
Tatyana V Golovkina
University of Chicago · US

Funding

VIRAL ONCOLOGY CORE FACILITYP30CA014599 · NCI · UNIVERSITY OF CHICAGO · PI MARK W. LINGEN · 1985 to 2026
$122.1M
ULTRASTRUCTURE AND CYTOMORPHOLOGY COREP30DK042086 · NIDDK · UNIVERSITY OF CHICAGO · PI LIU, CAMBRIAN YANGSHAO · 1990 to 2025
$29.8M
Retroviral Evasion of Immune ResponseR01AI090084 · NIAID · UNIVERSITY OF CHICAGO · PI GOLOVKINA, TATYANA V · 2012 to 2016
$2.1M
Retroviral evasion of immune responseR56AI090084 · NIAID · UNIVERSITY OF CHICAGO · PI GOLOVKINA, TATYANA V · 2010 to 2010
$428k
NCI NIH HHS P30 CA014599NCI NIH HHS P30CA014599NIAID NIH HHS AI090084NIAID NIH HHS R01 AI090084NIAID NIH HHS R56 AI090084NIDDK NIH HHS P30 DK042086
6 · The paper itself

Abstract

With our abilities to culture and sequence the commensal bacteria that dwell on and within a host, we can now study the host in its entirety, as a supraorganism that must be navigated by the pathogen invader. At present, the majority of studies have focused on the interaction between the host's microbiota and bacterial pathogens. This is not unwarranted, given that bacterial pathogens must compete with commensal organisms for the limited territory afforded by the host. However, viral pathogens also enter the host through surfaces coated with microbial life and encounter an immune system shaped by this symbiotic community. Therefore, we believe that the microbiota cannot be ignored when examining the interplay between the host and viral pathogens. Here, we review work that details mechanisms by which the microbiota either promotes or inhibits viral replication and virally induced pathogenesis. The impact of the microbitota on viral infection promises to be a new and exciting avenue of investigation, which will ultimately lead to better treatments and preventions of virally induced disease.

Indexed as

BacteriaBacterial Physiological PhenomenaSymbiosisAnimalsHost-Pathogen InteractionsHumansMetagenomeVirus DiseasesVirusesVirus Replicationgerm-free miceimmune responsemicrobiotaviruses

Identifiers

PMID23947358
PMCPMC3838194
OpenAlexW2149594315

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.