ReviewHealth research policy and systems2013
The financial burden from non-communicable diseases in low- and middle-income countries: a literature review.
Review in Health research policy and systems, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 210 papers, 16 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
210 citing papers in PubMed, 16 syntheses or guidelines pooled it, 397 citations in OpenAlex.
- Mapping the landscape of managed entry agreements: a systematic review of global frameworks, system-level components, and implementation challenges.Frontiers in pharmacology · 2026Pooled it
- The economic burden of ischaemic heart diseases on health systems: a systematic review.BMJ global health · 2025Pooled it
- Use of Preventable Risk Integrated Model on behavioral risk factors: a scoping review and bibliometric analysis.Frontiers in nutrition · 2025Pooled it
- A comparative systematic review of risk factors, prevalence, and challenges contributing to non-communicable diseases in South Asia, Africa, and Caribbeans.Journal of health, population, and nutrition · 2024Pooled it
- Health insurance status, lifestyle choices and the presence of non-communicable diseases: a systematic review.Journal of public health (Oxford, England) · 2024Pooled it
- Health seeking behaviours and private sector delivery of care for non-communicable diseases in low- and middle-income countries: a systematic review.BMC health services research · 2024Pooled it
- Barriers to cervical cancer and breast cancer screening uptake in low- and middle-income countries: a systematic review.Health policy and planning · 2023Pooled it
- The costs of interventions for type 2 diabetes mellitus, hypertension and cardiovascular disease in South Africa - a systematic literature review.BMC public health · 2022Pooled it
- The household financial burden of non-communicable diseases in low- and middle-income countries: a systematic review.Health research policy and systems · 2021Pooled it
- Models of care for patients with hypertension and diabetes in humanitarian crises: a systematic review.Health policy and planning · 2021Pooled it
- Pooled it
- The economic burden of cardiovascular disease and hypertension in low- and middle-income countries: a systematic review.BMC public health · 2018Pooled it
- Evaluating the impact of the national health insurance scheme of Ghana on out of pocket expenditures: a systematic review.BMC health services research · 2018Pooled it
- The economic impact of non-communicable diseases among households in South Asia and their coping strategy: A systematic review.PloS one · 2018Pooled it
- Provider costs for prevention and treatment of cardiovascular and related conditions in low- and middle-income countries: a systematic review.BMC public health · 2015Pooled it
- The global impact of non-communicable diseases on households and impoverishment: a systematic review.European journal of epidemiology · 2015Pooled it
- Equity impact of participatory learning and action community mobilisation and mHealth interventions to prevent and control type 2 diabetes and intermediate hyperglycaemia in rural Bangladesh: analysis of a cluster randomised controlled trial.Journal of epidemiology and community health · 2022Trial
- Human-centered design as a guide to intervention planning for non-communicable diseases: the BIGPIC study from Western Kenya.BMC health services research · 2020Trial
- Facilitators and Barriers to Chronic Disease Self-Management and Mobile Health Interventions for People Living With Diabetes and Hypertension in Cambodia: Qualitative Study.JMIR mHealth and uHealth · 2020Trial
- Economic evaluation of the practical approach to lung health and informal provider interventions for improving the detection of tuberculosis and chronic airways disease at primary care level in Malawi: study protocol for cost-effectiveness analysis.Implementation science : IS · 2015Trial
150 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-communicable diseases (NCDs) were previously considered to only affect high-income countries. However, they now account for a very large burden in terms of both mortality and morbidity in low- and middle-income countries (LMICs), although little is known about the impact these diseases have on households in these countries. In this paper, we present a literature review on the costs imposed by NCDs on households in LMICs. We examine both the costs of obtaining medical care and the costs associated with being unable to work, while discussing the methodological issues of particular studies. The results suggest that NCDs pose a heavy financial burden on many affected households; poor households are the most financially affected when they seek care. Medicines are usually the largest component of costs and the use of originator brand medicines leads to higher than necessary expenses. In particular, in the treatment of diabetes, insulin--when required--represents an important source of spending for patients and their families. These financial costs deter many people suffering from NCDs from seeking the care they need. The limited health insurance coverage for NCDs is reflected in the low proportions of patients claiming reimbursement and the low reimbursement rates in existing insurance schemes. The costs associated with lost income-earning opportunities are also significant for many households. Therefore, NCDs impose a substantial financial burden on many households, including the poor in low-income countries. The financial costs of obtaining care also impose insurmountable barriers to access for some people, which illustrates the urgency of improving financial risk protection in health in LMIC settings and ensuring that NCDs are taken into account in these systems. In this paper, we identify areas where further research is needed to have a better view of the costs incurred by households because of NCDs; namely, the extension of the geographical scope, the inclusion of certain diseases hitherto little studied, the introduction of a time dimension, and more comparisons with acute illnesses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.