ArticleTheranostics2013
Labeling human mesenchymal stem cells with gold nanocages for in vitro and in vivo tracking by two-photon microscopy and photoacoustic microscopy.
Article in Theranostics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed.
- Electrically switchable dual-focus metalens for depth-extended in vivo photoacoustic imaging of ophthalmic vascular disease.Light, science & applications · 2026Article
- Article
- Two-Photon Intravital Microscopy of Glioblastoma in a Murine Model.Journal of visualized experiments : JoVE · 2024Article
- Tumor-tropic Trojan horses: Using mesenchymal stem cells as cellular nanotheranostics.Theranostics · 2024Review
- Looking deep inside tissue with photoacoustic molecular probes: a review.Journal of biomedical optics · 2022Review
- Unveiling the improved targeting migration of mesenchymal stem cells with CXC chemokine receptor 3-modification using intravital NIR-II photoacoustic imaging.Journal of nanobiotechnology · 2022Article
- Nanotechnology-Assisted Cell Tracking.Nanomaterials (Basel, Switzerland) · 2022Review
- Nanomaterials as Ultrasound Theragnostic Tools for Heart Disease Treatment/Diagnosis.International journal of molecular sciences · 2022Review
- Contrast agents for photoacoustic imaging: a review of stem cell tracking.Stem cell research & therapy · 2021Review
- Seeing through the Skin: Photoacoustic Tomography of Skin Vasculature and Beyond.JID innovations : skin science from molecules to population health · 2021Review
- Integrating photoacoustic microscopy with other imaging technologies for multimodal imaging.Experimental biology and medicine (Maywood, N.J.) · 2021Review
- Bioprinted Injectable Hierarchically Porous Gelatin Methacryloyl Hydrogel Constructs with Shape-Memory Properties.Advanced functional materials · 2020Article
- Comprehensive Survey on Nanobiomaterials for Bone Tissue Engineering Applications.Nanomaterials (Basel, Switzerland) · 2020Review
- Article
- Photoacoustic Imaging in Tissue Engineering and Regenerative Medicine.Tissue engineering. Part B, Reviews · 2020Review
- Nanoparticle-based Cell Trackers for Biomedical Applications.Theranostics · 2020Review
- A Tumor-on-a-Chip System with Bioprinted Blood and Lymphatic Vessel Pair.Advanced functional materials · 2019Article
- Seeing Better and Going Deeper in Cancer Nanotheranostics.International journal of molecular sciences · 2019Review
- Photoacoustic and fluorescent effects in multilayer plasmon-dye interfaces.Journal of biophotonics · 2019Article
- Functional endoscopy techniques for tracking stem cell fate.Quantitative imaging in medicine and surgery · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Stem cell tracking is a highly important subject. Current techniques based on nanoparticle-labeling, such as magnetic resonance imaging, fluorescence microscopy, and micro-computed tomography, are plagued by limitations including relatively low sensitivity or penetration depth, involvement of ionizing irradiation, and potential cytotoxicity of the nanoparticles. Here we introduce a new class of contrast agents based on gold nanocages (AuNCs) with hollow interiors and porous walls to label human mesenchymal stem cells (hMSCs) for both in vitro and in vivo tracking using two-photon microscopy and photoacoustic microscopy. As demonstrated by the viability assay, the AuNCs showed negligible cytotoxicity under a reasonable dose, and did not alter the differentiation potential of the hMSCs into desired lineages. We were able to image the cells labeled with AuNCs in vitro for at least 28 days in culture, as well as to track the cells that homed to the tumor region in nude mice in vivo.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.