Evidence map›Paper›PMID 23946584›Full record

ArticleJournal of pharmacy & bioallied sciences2013

Pathogenesis and therapeutic intervention of oral submucous fibrosis.

Thukanaykanpalayam Ragunathan Yoithapprabhunath, Thangadurai Maheswaran, Janardhanam Dineshshankar, Abraham Anusushanth, Pandian Sindhuja, Govindasamy Sitra

Open access · goldAbstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Annals of translational medicine · 2021
    Article
  8. Use of Aloe Vera and Turmeric Paste as a Supplementary Medicine in Oral Submucosal Fibrosis: A Pilot Study.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2019
    Article
  9. Article
  10. Article
  11. Proposed new grading of oral submucous fibrosis based on cheek flexibility.Journal of clinical and experimental dentistry · 2014
    Article
  12. Article
  13. Article
  14. Article
  15. Medical management of oral submucous fibrosis.Asia-Pacific journal of oncology nursing
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Thukanaykanpalayam Ragunathan YoithapprabhunathDepartment of Oral Pathology, Vivekanandha Dental College for Women, Tiruchengodu, Tamil Nadu, India.
Thangadurai Maheswaran
Janardhanam Dineshshankar
Abraham Anusushanth
Pandian Sindhuja
Govindasamy Sitra
Vokkaligara Sangha Dental College & Hospital · INNoorul Islam College of Dental Science · INRagas Dental College & Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral submucous fibrosis (OSF) is a chronic, progressive, potentially malignant condition affecting the oral cavity and frequently involving the upper part of the aerodigestive tract including the oropharynx and the upper part of the esophagus. It is characterized by juxtaepithelial inflammatory reaction and progressive fibrosis of lamina propria, leading to stiffening of the oral mucosa eventually causing trismus. This condition is associated with significant morbidity and high risk of malignancy. Over the years, several drugs and combinations have been tried for the treatment of submucous fibrosis, but with limited success, because of its unclear molecular pathogenesis. Till date, there are no known effective treatments for OSF. The aim of this article is to emphasize on the molecular changes taking place in OSF and possible therapeutic interventions.

Indexed as

Classificationoral submucous fibrosispathogenesistreatment

Identifiers

PMID23946584
PMCPMC3722713
OpenAlexW2036394128

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.