ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2013
Proactive selective response suppression is implemented via the basal ganglia.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 1 of them a synthesis that pooled it.
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Who cites it
79 citing papers in PubMed, 1 synthesis or guideline pooled it, 147 citations in OpenAlex.
- The effect of task complexity on the neural network for response inhibition: An ALE meta-analysis.Neuroscience and biobehavioral reviews · 2024Pooled it
- Feasibility and effects of cognitive training on cognition and psychosocial function in Huntington's disease: a randomised pilot trial.Journal of neurology · 2025Trial
- Trial
- Training-induced changes in inhibitory control network activity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Trial
- Distinct temporal patterns of beta bursts differentiate successful and failed movement cancellation.iScience · 2026Article
- Functional connectivity between the caudate nucleus and the frontal lobe and its association with executive functions in children and adolescents: a resting state fMRI study.Brain imaging and behavior · 2026Article
- Dynamic modeling in neurocognitive frameworks of childhood ADHD: a review of inhibitory control and reward systems.Translational psychiatry · 2026Review
- Frontal theta power prospectively associated with response inhibition.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- Dynamic Neural Deactivation Bridges Direct and Competitive Inhibition Processes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Enhancing Human Action Inhibition Through Cortico-Cortical Paired Associative Stimulation.Annals of the New York Academy of Sciences · 2025Article
- Brain mechanisms underlying the inhibitory control of thought.Nature reviews. Neuroscience · 2025Review
- Involvement of Neurons in the Nonhuman Primate Anterior Striatum in Proactive Inhibition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Involvement of neurons in the non-human primate anterior striatum in proactive inhibition.bioRxiv : the preprint server for biology · 2024Article
- Failing to attend versus failing to stop: Single-trial decomposition of action-stopping in the stop signal task.Behavior research methods · 2023Article
- Neural mechanisms of domain-general inhibitory control.Trends in cognitive sciences · 2023Review
- Snapping Out of Autopilot: Overriding Habits in Real Time and the Role of Ventrolateral Prefrontal Cortex.Perspectives on psychological science : a journal of the Association for Psychological Science · 2023Article
- Proactive Interhemispheric Disinhibition Supports Response Preparation during Selective Stopping.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Prepared and reactive inhibition in smokers and non-smokers.Behavioural brain research · 2023Article
- Is motor inhibition involved in the processing of sentential negation? An assessment via the Stop-Signal Task.Psychological research · 2023Article
- Investigating the role of contextual cues and interhemispheric inhibitory mechanisms in response-selective stopping: a TMS study.Cognitive, affective & behavioral neuroscience · 2023Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
In the welter of everyday life, people can stop particular response tendencies without affecting others. A key requirement for such selective suppression is that subjects know in advance which responses need stopping. We hypothesized that proactively setting up and implementing selective suppression relies on the basal ganglia and, specifically, regions consistent with the inhibitory indirect pathway for which there is scant functional evidence in humans. Consistent with this hypothesis, we show, first, that the degree of proactive motor suppression when preparing to stop selectively (indexed by transcranial magnetic stimulation) corresponds to striatal, pallidal, and frontal activation (indexed by functional MRI). Second, we demonstrate that greater striatal activation at the time of selective stopping correlates with greater behavioral selectivity. Third, we show that people with striatal and pallidal volume reductions (those with premanifest Huntington's disease) have both absent proactive motor suppression and impaired behavioral selectivity when stopping. Thus, stopping goals are used to proactively set up specific basal ganglia channels that may then be triggered to implement selective suppression. By linking this suppression to the striatum and pallidum, these results provide compelling functional evidence in humans of the basal ganglia's inhibitory indirect pathway.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.