Evidence map›Paper›PMID 23946311›Full record

ArticleNeurology2013

Both low and high temperature may increase the risk of stroke mortality.

Renjie Chen, Cuicui Wang, Xia Meng, Honglei Chen, Thuan Quoc Thach, Chit-Ming Wong, Haidong Kan

Abstract read
In one paragraph

Article in Neurology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Short-Term Effect of Ambient Temperature and the Risk of Stroke: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2015
    Pooled it
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  5. Stroke and climate change: A World Stroke Organization scientific statement.International journal of stroke : official journal of the International Stroke Society · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Renjie ChenFrom the School of Public Health, Key Lab of Public Health Safety of the Ministry of Education (R.C., C.W., X.M., H.K.), Research Institute for the Changing Global Environment and Fudan Tyndall Centre (R.C., C.W., X.M., H.K.), and Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention (LAP) (R.C., C.W., X.M., H.K.), Fudan University, Shanghai, China; Epidemiology Branch (H.C.), National Institute of Environmental Health Science, National Institutes of Health, Research Triangle Park, NC; and Department of Community Medicine (T.Q.T., C.-M.W.), School of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Cuicui Wang
Xia Meng
Honglei Chen
Thuan Quoc Thach
Chit-Ming Wong
Haidong Kan

Funding

Prospective studies on Parkinson's diseaseZIAES101986 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI CHEN, HONGLEI · 2009 to 2016
$7.9M
Intramural NIH HHS
6 · The paper itself

Abstract

objectiveTo examine temperature in relation to stroke mortality in a multicity time series study in China.

methodsWe obtained data on daily temperature and mortality from 8 large cities in China. We used quasi-Poisson generalized additive models and distributed lag nonlinear models to estimate the accumulative effects of temperature on stroke mortality across multiple days, adjusting for long-term and seasonal trends, day of the week, air pollution, and relative humidity. We applied the Bayesian hierarchical model to pool city-specific effect estimates.

resultsBoth cold and hot temperatures were associated with increased risk of stroke mortality. The potential effect of cold temperature might last more than 2 weeks. The pooled relative risks of extreme cold (first percentile of temperature) and cold (10th percentile of temperature) temperatures over lags 0-14 days were 1.39 (95% posterior intervals [PI] 1.18-1.64) and 1.11 (95% PI 1.06-1.17), compared with the 25th percentile of temperature. In contrast, the effect of hot temperature was more immediate. The relative risks of stroke mortality over lags 0-3 days were 1.06 (95% PI 1.02-1.10) for extreme hot temperature (99th percentile of temperature) and 1.14 (95% PI 1.05-1.24) for hot temperature (90th percentile of temperature), compared with the 75th percentile of temperature.

conclusionsThis study showed that both cold and hot temperatures were associated with increased risk of stroke mortality in China. Our findings may have important implications for stroke prevention in China.

Indexed as

Air PollutantsChinaCold TemperatureHot TemperatureHumansSeasonsStrokeTime FactorsAir Pollutants

Identifiers

PMID23946311
PMCPMC3795588

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.