Evidence map›Paper›PMID 23946052›Full record

ArticleAngewandte Chemie (International ed. in English)2013

Efficient detection of hydrogen bonds in dynamic regions of RNA by sensitivity-optimized NMR pulse sequences.

Andre Dallmann, Bernd Simon, Malgorzata M Duszczyk, Hamed Kooshapur, Arthur Pardi, Wolfgang Bermel, Michael Sattler

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Application of NMR to Large RNAs.Journal of molecular biology · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Imino chemical shift assignments of tRNABiomolecular NMR assignments · 2024
    Article
  8. Structure of pre-miR-31 reveals an active role in Dicer-TRBP complex processing.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  9. Pressure pushes tRNAProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  10. Structure of pre-miR-31 reveals an active role in Dicer processing.bioRxiv : the preprint server for biology · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andre DallmannInstitute of Structural Biology, Helmholtz Zentrum München, Ingolstädter Landstr. 1, 85764 Neuherberg (Germany) http://www.nmr.ch.tum.de/; Center for Integrated Protein Science Munich and Chair of Biomolecular NMR, TU München, Lichtenbergstr. 4, 85747 Garching (Germany).
Bernd Simon
Malgorzata M Duszczyk
Hamed Kooshapur
Arthur Pardi
Wolfgang Bermel
Michael Sattler

Funding

Structure and Dynamics of RNA and Protein-RNA ComplexesR01GM086862 · NIGMS · UNIVERSITY OF COLORADO · PI PARDI, ARTHUR · 2009 to 2012
$1.3M
NIGMS NIH HHS GM086862NIGMS NIH HHS R01 GM086862
6 · The paper itself

Abstract

Improved Sensitivity: Efficient NMR experiments are presented for determining the secondary structure in large and dynamic RNAs using J-couplings across hydrogen bonds. The experiments provide up to eight-fold improved sensitivity and thus enable detection of base pairs in dynamic regions even in large RNAs.

Indexed as

Base SequenceHydrogen BondingMolecular Sequence DataMolecular WeightNuclear Magnetic Resonance, BiomolecularNucleic Acid ConformationRNARNAbase pairshydrogen bondsNMR spectroscopyRNA dynamicsRNA secondary structure

Identifiers

PMID23946052
PMCPMC3882076

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.