ArticleJournal of neurophysiology2013
Dendritic mechanisms contribute to stimulus-specific adaptation in an insect neuron.
Article in Journal of neurophysiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 16 citations in OpenAlex.
- Neuronal processing of complex sounds in the prothoracic ganglion of a bushcricket.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Article
- Tonotopic CaJournal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2024Article
- Temporal processing properties of auditory DUM neurons in a bush-cricket.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2019Article
- Evolutionarily conserved coding properties favour the neuronal representation of heterospecific signals of a sympatric katydid species.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2018Article
- Dendritic CaJournal of neurophysiology · 2018Article
- Direction-Specific Adaptation in Neuronal and Behavioral Responses of an Insect Mechanosensory System.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Neural Mechanisms for Acoustic Signal Detection under Strong Masking in an Insect.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Dynamic dendritic compartmentalization underlies stimulus-specific adaptation in an insect neuron.Journal of neurophysiology · 2015Article
- Neurobiology of acoustically mediated predator detection.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Reduced neuronal activation to repetitive stimulation is a common feature of information processing in nervous systems. Such stimulus-specific adaptation (SSA) occurs in many systems, but the underlying neural mechanisms are not well understood. The Neoconocephalus (Orthoptera, Tettigoniidae) TN-1 auditory neuron exhibits an SSA-like process, characterized by reliably detecting deviant pulses after response cessation to common standard pulses. Therefore, TN-1 provides a model system to study the cellular mechanisms underlying SSA with an identified neuron. Here we test the hypothesis that dendritic mechanisms underlie TN-1 response cessation to fast-pulse rate repeated signals. Electrically stimulating TN-1 with either high-rate or continuous-current pulses resulted in a decreased ability in TN-1 to generate action potentials but failed to elicit cessation of spiking activity as observed with acoustic stimulation. BAPTA injection into TN-1 delayed the onset of response cessation to fast-pulse rate acoustic stimuli in TN-1 but did not eliminate it. These results indicate that calcium-mediated processes contribute to the fast cessation of spiking activity in TN-1 but are insufficient to cause spike cessation on its own. Replacing normal saline with low-Na(+) saline (replacing sodium chloride with either lithium chloride or choline chloride) eliminated response cessation, and TN-1 no longer responded selectively to the deviant pulses. Sodium-mediated potassium channels are the most likely candidates underlying sodium-mediated response suppression in TN-1, triggered by Na(+) influx in dendritic regions activated by acoustic stimuli. On the basis of these results, we present a model for a cellular mechanism for SSA in a single auditory neuron.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.