Trial reportThe American journal of clinical nutrition2013
Effects of an intervention to promote breastfeeding on maternal adiposity and blood pressure at 11.5 y postpartum: results from the Promotion of Breastfeeding Intervention Trial, a cluster-randomized controlled trial.
Trial report in The American journal of clinical nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01561612 (Breastfeeding Promotion RCT and Child Metabolic Syndrome), which is not on this map. Cited by 31 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Breastfeeding Promotion RCT and Child Metabolic Syndrome
Who cites it
31 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Support for healthy breastfeeding mothers with healthy term babies.The Cochrane database of systematic reviews · 2022Pooled it
- Support for healthy breastfeeding mothers with healthy term babies.The Cochrane database of systematic reviews · 2017Pooled it
- Breastfeeding and maternal cardiovascular risk factors and outcomes: A systematic review.PloS one · 2017Pooled it
- Breastfeeding initiation and duration among people with mild chronic hypertension: a secondary analysis of the Chronic Hypertension and Pregnancy trial.American journal of obstetrics & gynecology MFM · 2023Trial
- Causal effects of breastfeeding promotion on child health: understanding the role of nutrition.Swiss journal of economics and statistics · 2026Article
- Breastfeeding History and Maternal Body Composition Indicators: A Scoping Review.Current nutrition reports · 2025Article
- Prospective associations between breast feeding, metabolic health, inflammation and bone density in women with prior gestational diabetes mellitus.BMJ open diabetes research & care · 2024Article
- Association of breastfeeding duration with overweight and obesity among women in Ghana.Frontiers in global women's health · 2024Article
- Estimating carbon and water footprints associated with commercial milk formula production and use: development and implications of the Green Feeding Climate Action Tool.Frontiers in nutrition · 2024Review
- Association of Handgrip Strength and Cardiovascular Disease Risk Among Middle-Aged Postmenopausal Women: An Analysis of the Korea National Health and Nutrition Examination Survey 2014-2019.Vascular health and risk management · 2024Article
- Article
- Effectiveness of breastfeeding education compared to standard hospital information on exclusive breastfeeding among mothers: A systematic review.Journal of education and health promotion · 2022Review
- Analysis of Maternal Prenatal Weight and Offspring Cognition and Behavior: Results From the Promotion of Breastfeeding Intervention Trial (PROBIT) Cohort.JAMA network open · 2021Article
- Breastfeeding history and the risk of overweight and obesity in middle-aged women.BMC women's health · 2021Article
- Lifetime duration of lactation and chronic inflammation among middle-aged women with a history of gestational diabetes.BMJ open diabetes research & care · 2020Article
- Lactation and Maternal Subclinical Atherosclerosis Among Women With and Without a History of Hypertensive Disorders of Pregnancy.Journal of women's health (2002) · 2020Article
- Caregiver Influences on Eating Behaviors in Young Children: A Scientific Statement From the American Heart Association.Journal of the American Heart Association · 2020Review
- Breastfeeding and maternal cardiovascular risk factors: 1982 Pelotas Birth Cohort.Scientific reports · 2019Article
- Lifestyle intervention strategies in early life to improve pregnancy outcomes and long-term health of offspring: a narrative review.Journal of developmental origins of health and disease · 2019Review
- The effect of breastfeeding on postpartum glucose tolerance and lipid profiles in women with gestational diabetes mellitus.International breastfeeding journal · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundDifferences between mothers who do and do not succeed in breastfeeding are likely to confound associations of lactation with later maternal adiposity.
objectiveWe compared adiposity and blood pressure (BP) in women randomly assigned to an intervention to promote prolonged and exclusive breastfeeding or usual care.
designWe performed a cluster-randomized trial at 31 hospitals in Belarus in 1996-1997.
resultsOf 17,046 women enrolled at delivery, we assessed 11,867 women (69.6%) at 11.5 y postpartum. The prevalence of exclusive breastfeeding ≥3 mo was 44.5% in 6321 women in the intervention group and 7.1% in 5546 women in the control group. At 11.5 y postpartum, mean (±SD) body mass index (BMI; in kg/m(2)) was 26.5 ± 5.5, the percentage of body fat was 33.6% ± 8.3%, and systolic BP was 124.6 ± 14.6 mm Hg. On intention-to-treat analysis (without imputation) with adjustment for clustering by hospital, mean outcomes were lower in intervention compared with control mothers for BMI (mean difference: -0.27; 95% CI: -0.91, 0.37), body fat (-0.49%; 95% CI: -1.25%, 0.27%), and systolic BP (-0.81 mm Hg; 95% CI: -3.33, 1.71 mm Hg), but effect sizes were small, CIs were wide, and results were attenuated further toward the null after adjustment for baseline characteristics. Results were similar in sensitivity analyses [ie, by using conventional observational analyses disregarding treatment assignment, instrumental variable analyses to estimate the causal effect of breastfeeding, and multiple imputation to account for missing outcome measures (n = 17,046)].
conclusionIn women who initiated breastfeeding, an intervention to promote longer breastfeeding duration did not result in an important lowering of adiposity or BP. This trial was registered at clinicaltrials.gov as NCT01561612 and at Current Controlled Trials as ISRCTN37687716.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.