ArticleAJNR. American journal of neuroradiology2014
Coiling of large and giant aneurysms: complications and long-term results of 334 cases.
Article in AJNR. American journal of neuroradiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06134557 (Analysis of the Therapeutic Effect of Blood Flow Reconstruction in the Treatment of Intracranial Dissection Aneurysm of Vertebral Artery), which is not on this map. Cited by 55 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Analysis of the Therapeutic Effect of Blood Flow Reconstruction in the Treatment of Intracranial Dissection Aneurysm of Vertebral Artery
Who cites it
55 citing papers in PubMed, 2 syntheses or guidelines pooled it, 136 citations in OpenAlex.
- Safety and effectiveness of endoscopic endonasal intracranial aneurysm clipping: a systematic review.Neurosurgical review · 2021Pooled it
- Efficacy and safety of PulseRider for treatment of wide-necked intracranial aneurysm-A systematic review and meta-analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2021Pooled it
- Trial
- Parent Artery Reconstruction for Large or Giant Cerebral Aneurysms Using the Tubridge Flow Diverter: A Multicenter, Randomized, Controlled Clinical Trial (PARAT).AJNR. American journal of neuroradiology · 2018Trial
- HydroCoils reduce recurrence rates in recently ruptured medium-sized intracranial aneurysms: a subgroup analysis of the HELPS trial.AJNR. American journal of neuroradiology · 2015Trial
- Comparison of the Safety and Efficacy between Endovascular Coiling and Surgical Clipping of Posterior Communicating Artery Aneurysms: A 10-year Retrospective Analysis of 851 Aneurysms.Neurologia medico-chirurgica · 2026Article
- Application of machine learning algorithms to predict and assess factors related to internal carotid siphon aneurysm occlusion treated with flow diversion.Neuroradiology · 2026Article
- Safety and efficacy of the fourth-generation Acandis Acclino flex plus stent for the treatment of complex intracranial aneurysms.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026Article
- Double-barrel STA-MCA bypass with endovascular parent artery occlusion for complex anterior circulation aneurysms: indications and outcomes.Acta neurochirurgica · 2026Observational
- Flow Diversion vs. Coiling for Large and Giant Intracranial Aneurysms: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- Efficacy and safety of fetal posterior cerebral artery stented coil embolization for fetal posterior cerebral aneurysms.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Largest documented cerebral aneurysm mimicking a giant brain tumor and treated by highly selective occlusion of inflow: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Role and Safety of Tirofiban in Peri-Interventional Antiplatelet Management for Aneurysm Treatment.Clinical neuroradiology · 2025Article
- Comparison of coiling followed by staged-flow diversion and flow diversion-assisted coiling for intracranial very large and giant aneurysms of the internal carotid artery.Neurosurgical review · 2025Article
- Investigating Delayed Rupture of Flow Diverter-Treated Giant Aneurysm Using Simulated Fluid-Structure Interactions.Bioengineering (Basel, Switzerland) · 2025Article
- Strategic Dual Approach for the Management of a Symptomatic Giant Partially Thrombosed Aneurysm at the Basilar Tip - Integrating Intrasaccular Flow Diversion and Endovascular Flow Reversal.Journal of Korean Neurosurgical Society · 2025Article
- Safety and efficacy of short-term tirofiban combined with dual antiplatelet therapy after flow diverter placement for intracranial aneurysms: a multicenter retrospective study and nomogram for thromboembolic event prediction.Frontiers in neurology · 2025Article
- Large and giant intracranial aneurysms: outcomes from the multicenter prospective SMART coils registry.Frontiers in neurology · 2025Article
- Multicenter Experience with the Pipeline Flex and Vantage with Shield Technology for Intracranial Aneurysm Treatment.AJNR. American journal of neuroradiology · 2024Observational
- Risk Factors and Clinical Significance of Ultra-Long-Term Microischemia After Intracranial Aneurysm Embolization.Neurology and therapy · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeLarge and giant intracranial aneurysms are increasingly treated with endovascular techniques. The goal of this study was to retrospectively analyze the complications and long-term results of coiling in large and giant aneurysms (≥ 10 mm) and identify predictors of outcome. MATERIALS AND
methodsA total of 334 large or giant aneurysms (≥ 10 mm) were coiled in our institution between 2004 and 2011. Medical charts and imaging studies were reviewed to determine baseline characteristics, procedural complications, and clinical/angiographic outcomes. Aneurysm size was 15 mm on average. Two hundred twenty-five aneurysms were treated with conventional coiling; 88, with stent-assisted coiling; 14, with parent vessel occlusion; and 7, with balloon-assisted coiling.
resultsComplications occurred in 10.5% of patients, with 1 death (0.3%). Aneurysm location and ruptured aneurysms predicted complications. Angiographic follow-up was available for 84% of patients at 25.4 months on average. Recanalization and retreatment rates were 39% and 33%, respectively. Larger aneurysm size, increasing follow-up time, conventional coiling, and aneurysm location predicted both recurrence and retreatment. The annual rebleeding rate was 1.9%. Larger aneurysm size, increasing follow-up time, and aneurysm location predicted new or recurrent hemorrhage. Favorable outcomes occurred in 92% of patients. Larger aneurysm size, poor Hunt and Hess grades, and new or recurrent hemorrhage predicted poor outcome.
conclusionsCoiling of large and giant aneurysms has a reasonable safety profile with good clinical outcomes, but aneurysm reopening remains very common. Stent-assisted coiling has lower recurrence, retreatment, and new or recurrent hemorrhage rates with no additional morbidity compared with conventional coiling. Aneurysm size was a major determinant of recanalization, retreatment, new or recurrent hemorrhage, and poor outcome.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.