Evidence map›Paper›PMID 23943570›Full record

ArticleAngewandte Chemie (International ed. in English)2013

DNA modification under mild conditions by Suzuki-Miyaura cross-coupling for the generation of functional probes.

Lukas Lercher, Joanna F McGouran, Benedikt M Kessler, Christopher J Schofield, Benjamin G Davis

Open access · bronzeAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 126 citations in OpenAlex.

  1. Article
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  5. Review
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  7. Oligonucleotide Bioconjugation with Bifunctional Palladium Reagents.Angewandte Chemie (International ed. in English) · 2021
    Article
  8. Article
  9. Article
  10. Bioorthogonal chemistry.Nature reviews. Methods primers · 2021
    Article
  11. Article
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  13. Article
  14. Article
  15. Article
  16. Arylation Chemistry for Bioconjugation.Angewandte Chemie (International ed. in English) · 2019
    Review
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lukas LercherDepartment of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA (UK).
Joanna F McGouran
Benedikt M Kessler
Christopher J Schofield
Benjamin G Davis
University of Oxford · GB

Funding

Biotechnology and Biological Sciences Research Council BB/E004350/1Biotechnology and Biological Sciences Research Council EGA17763
6 · The paper itself

Abstract

Quick and clean: A method for Pd-catalyzed Suzuki-Miyaura cross-coupling to iododeoxyuridine (IdU) in DNA is described. Key to the reactivity is the choice of the ligand and the buffer. A covalent [Pd]-DNA intermediate was isolated and characterized. Photocrosslinking probes were generated to trap proteins that bind to epigenetic DNA modifications.

Indexed as

CatalysisDNAIdoxuridineMolecular ProbesOligonucleotidesPalladiumPhotoaffinity LabelsDNAIdoxuridineMolecular ProbesOligonucleotidesPalladiumPhotoaffinity Labelscross-couplingDNAoligonucleotidespalladiumphotoaffinity labeling

Identifiers

PMID23943570
PMCPMC3823066
OpenAlexW2159104257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.