Evidence map›Paper›PMID 23943404›Full record

ArticleMycopathologia2013

Feline nasal granuloma due to Cryptoccocus gattii type VGII.

Pedro Henrique Magalhães Cardoso, Francisco de Assis Baroni, Eriques Gonçalves Silva, Diana Costa Nascimento, Marilena Dos Anjos Martins, Walderez Szezs, Claudete Rodrigues Paula

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Mycopathologia, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Journal of fungi (Basel, Switzerland) · 2021
    Article
  3. Journal of fungi (Basel, Switzerland) · 2021
    Review
  4. Cryptococcosis due toMedical mycology case reports · 2019
    Article
  5. Pathologic, histochemical, and immunohistochemical findings in pulmonary and encephalitic cryptococcosis in a goat.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2019
    Article
  6. The status of cryptococcosis in Latin America.Memorias do Instituto Oswaldo Cruz · 2018
    Review
  7. Review
  8. Molecular characterisation and antifungal susceptibility of clinical Cryptococcus deuterogattii (AFLP6/VGII) isolates from Southern Brazil.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2016
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Pedro Henrique Magalhães CardosoDepartamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, USP, São Paulo, Brazil.
Francisco de Assis Baroni
Eriques Gonçalves Silva
Diana Costa Nascimento
Marilena Dos Anjos Martins
Walderez Szezs
Claudete Rodrigues Paula
Hospital Universitário da Universidade de São Paulo · BRInstituto Adolfo Lutz · BRUniversidade de São Paulo · BRUniversidade Federal Rural do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aims of this study are to make a more precise identification of the etiologic agent of a nasal granuloma in a cat, to verify the susceptibility to the antifungal drugs: ketoconazole, itraconazole, fluconazole, posaconazole, voriconazole, amphotericin B and the proper treatment. Part of the granuloma's fragment was removed, added to a saline solution and sent to the Laboratory of Mycology. The solution was then seeded in Sabouraud dextrose agar, and the yeast was primarily identified by the traditional methods. The confirmation of the specie Cryptococcus gattii and its molecular type were performed using the PCR-RFLP molecular techniques. The antifungal susceptibility was verified by using the E-test method, and the cat was treated with itraconazole associated with 5-flucytosine. The isolated strain was identified as C. gattii type VGII and was susceptible to all antifungal drugs tested. The treatment with itraconazole associated with 5-flucytosine led to the cure of granulomatous lesions in the feline after 6 months. The characterization and molecular investigation of this microorganism are relevant because they could help us better understand the epidemiology of the infection and to guide us to treat properly the disease.

Indexed as

AnimalsAntifungal AgentsCat DiseasesCatsCryptococcosisCryptococcus gattiiFlucytosineGranulomaItraconazoleMicrobial Sensitivity TestsMicrobiological TechniquesMolecular Diagnostic TechniquesNose DiseasesTreatment OutcomeAntifungal AgentsFlucytosineItraconazole

Identifiers

PMID23943404
OpenAlexW2037405573

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.