ArticleEcotoxicology (London, England)2013
Antioxidant response and histopathological changes in brain tissue of pigeon exposed to avermectin.
Article in Ecotoxicology (London, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 52 citations in OpenAlex.
- Evaluation of the safety and insecticidal efficacy of ivermectin-treated bird feed formulations in different avian species.Parasites & vectors · 2026Article
- Comparative evaluation of haemato-biochemical and oxidative stress markers in natural patent and latent infection ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025Article
- Article
- Aberrant Gene Expression of Selenoproteins in Chicken Spleen Lymphocytes Induced by Mercuric Chloride.Biological trace element research · 2022Article
- Assessment of Avermectins-Induced Toxicity in Animals.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Effect of sublethal concentrations of the antiparasitic ivermectin on the polychaeta species Hediste diversicolor: biochemical and behavioral responses.Ecotoxicology (London, England) · 2021Article
- Effects of two kinds of fishery drugs on the expressions of GAD and GABA-T mRNA in crucian carp (Carassius auratus gibelio).Fish physiology and biochemistry · 2020Article
- Evaluation of a novel West Nile virus transmission control strategy that targets Culex tarsalis with endectocide-containing blood meals.PLoS neglected tropical diseases · 2019Article
- Effects of ivermectin on Danio rerio: a multiple endpoint approach: behaviour, weight and subcellular markers.Ecotoxicology (London, England) · 2016Article
- Effects of treatment with the anti-parasitic drug diminazene aceturate on antioxidant enzymes in rat liver and kidney.Naunyn-Schmiedeberg's archives of pharmacology · 2016Article
- Neuro and renal toxicity induced by chlorpyrifos and abamectin in rats: Toxicity of insecticide mixture.Environmental science and pollution research international · 2016Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Avermectins (AVMs) are the active components of some insecticidal and nematicidal products used in agriculture and veterinary medicine for the prevention of parasitic diseases. Residues of AVM drugs or their metabolites in livestock feces have toxic effects on non-target aquatic and terrestrial organisms. In this study, oxidative stress responses and pathological changes on pigeon brain tissues and serum after subchronic exposure to AVM for 30, 60 and 90 days were investigated. The decrease in antioxidant enzyme (superoxide dismutase, SOD and glutathione peroxidase, GSH-Px) activities and increase in methane dicarboxylic aldehyde content in a dose-time-dependent manner in the brain and serum of pigeon were observed. The protein carbonyl content, an indicator of protein oxidation, and DNA-protein crosslink coefficient were significantly augmented with dose-time-dependent properties. The microscopic structures of the cerebrum, cerebellum and optic lobe altered obviously, the severity of which increased with the concentration of AVM and exposure time. The results imply that AVM could induce oxidative damage to the brain tissue and serum of pigeon. The information presented in this study is helpful to understand the mechanism of AVM-induced oxidative stress in birds.
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