Evidence map›Paper›PMID 23943062›Full record

ArticleJournal of materials science. Materials in medicine2013

Mineralized collagen coatings formed by electrochemical deposition.

Ting Ling, Jun Lin, Junjun Tu, Siqian Liu, Wenjian Weng, Kui Cheng, Huiming Wang, Piyi Du, Gaorong Han

Abstract read
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In one paragraph

Article in Journal of materials science. Materials in medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Redox Is a Global Biodevice Information Processing Modality.Proceedings of the IEEE. Institute of Electrical and Electronics Engineers · 2019
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ting LingDepartment of Materials Science and Engineering, State Key Laboratory of Silicon Materials, Zhejiang University, Hangzhou, 310027, China.
Jun Lin
Junjun Tu
Siqian Liu
Wenjian Weng
Kui Cheng
Huiming Wang
Piyi Du
Gaorong Han

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding and controlling the process of electrochemical deposition (ECD) of a mineralized collagen coating on metallic orthopedic implants is important for engineering highly bioactive coatings. In this work, the influence of different ECD parameters was investigated. The results showed that the mineralization degree of the coatings increased with deposition time, voltage potential and H2O2 addition, while chitosan addition led to weakening of mineralization, heavy mineralization resulted in a porous coating morphology. Furthermore, two typical coatings, dense and porous, were analyzed to investigate their microstructure and evaluated for their cytocompatibility; the dense coating showed better osteoblast adhesion and proliferation. Based on our understanding of how the different coating parameters influenced the coating, we proposed an ECD process in which the pH gradient near the cathode and the collagen isoelectric point were suggested to play crucial roles in controlling the mineralization and morphology of the coatings. The proposed ECD process may offer a guide for controlled deposition of a desired bioactive coating.

Indexed as

3T3 CellsAnimalsCattleCell AdhesionCell ProliferationChitosanCoated Materials, BiocompatibleCollagenElectrochemistryHydrogen-Ion ConcentrationHydrogen PeroxideIsoelectric PointMiceOsteoblastsChitosanCoated Materials, BiocompatibleCollagenHydrogen Peroxide

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.