Evidence map›Paper›PMID 23942847›Full record

ReviewJournal of autism and developmental disorders2015

Eyeblink conditioning: a non-invasive biomarker for neurodevelopmental disorders.

Bethany C Reeb-Sutherland, Nathan A Fox

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of autism and developmental disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Review
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  4. Review
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  8. Mice lackingProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Mice lackingbioRxiv : the preprint server for biology · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
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  18. Young Domestic PigsFrontiers in behavioral neuroscience · 2021
    Article
  19. Article
  20. Consensus Paper: Cerebellum and Social Cognition.Cerebellum (London, England) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Bethany C Reeb-SutherlandDepartment of Psychology, DM 256, Florida International University, 11200 SW 8th Street, Miami, FL, 33199, USA, besuther@fiu.edu.
Nathan A Fox

Funding

Neurodevelopmental Mechanisms of Social BehaviorR01MH080759 · NIMH · VANDERBILT UNIVERSITY · PI LEVITT, PAT · 2007 to 2011
$3.0M
NIMH NIH HHS MH 080759
6 · The paper itself

Abstract

Eyeblink conditioning (EBC) is a classical conditioning paradigm typically used to study the underlying neural processes of learning and memory. EBC has a well-defined neural circuitry, is non-invasive, and can be employed in human infants shortly after birth making it an ideal tool to use in both developing and special populations. In addition, abnormalities in the cerebellum, a region of the brain highly involved in EBC, have been implicated in a number of neurodevelopmental disorders including autism spectrum disorders (ASDs). In the current paper, we review studies that have employed EBC as a biomarker for several neurodevelopmental disorders including fetal alcohol syndrome, Down syndrome, fragile X syndrome, attention deficit/hyperactivity disorder, dyslexia, specific language impairment, and schizophrenia. In addition, we discuss the benefits of using such a tool in individuals with ASD.

Indexed as

BiomarkersBrainChild DevelopmentChild Development Disorders, PervasiveConditioning, EyelidDevelopmental DisabilitiesHumansInfantNeural PathwaysBiomarkers

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.