Evidence map›Paper›PMID 23942828›Full record

GuidelineRheumatology international2014

German guidelines for the sequential medical treatment of rheumatoid arthritis with traditional and biologic disease-modifying antirheumatic drugs.

Katinka Albrecht, Klaus Krüger, Jürgen Wollenhaupt, Rieke Alten, Marina Backhaus, Christoph Baerwald, Wolfgang Bolten, Jürgen Braun, Harald Burkhardt, Gerd R Burmester and 18 more

Abstract readPractice GuidelineReview
PubMed Publisher
In one paragraph

Guideline in Rheumatology international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Translating IL-6 biology into effective treatments.Nature reviews. Rheumatology · 2020
    Review
  5. Article
  6. Observational
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  8. Observational
  9. Review
  10. Article
  11. Article
  12. Article
  13. Observational
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 20 institutions in 1 country.

Katinka AlbrechtGerman Society of Rheumatology, Berlin, Germany, katinka.albrecht@dgrh.de.
Klaus Krüger
Jürgen Wollenhaupt
Rieke Alten
Marina Backhaus
Christoph Baerwald
Wolfgang Bolten
Jürgen Braun
Harald Burkhardt
Gerd R Burmester
Markus Gaubitz
Angela Gause
Erika Gromnica-Ihle
Herbert Kellner
Jens Kuipers
Andreas Krause
Hans-Martin Lorenz
Bernhard Manger
Hubert Nüßlein
Hans-Georg Pott
Andrea Rubbert-Roth
Matthias Schneider
Christof Specker
Hendrik Schulze-Koops
Hans-Peter Tony
Siegfried Wassenberg
Ulf Müller-Ladner
German Society of Rheumatology
Charité - Universitätsmedizin Berlin · DEFachklinik 360° · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEGerman Centre of Gerontology · DEGerman Society of Surgery · DEGoethe University Frankfurt · DEHeidelberg University · DEHeinrich Heine University Düsseldorf · DEHumboldt-Universität zu Berlin · DEImmanuel Krankenhaus · DEKerckhoff Klinik · DEKliniken Essen-Mitte · DEKrankenhaus vom Roten Kreuz · DELeipzig University · DELMU Klinikum · DEMEDIAN Klaus-Miehlke-Klinik Wiesbaden · DEMedizinische Hochschule Hannover · DENuremberg Hospital · DESchlosspark-Klinik · DESt. Josef-Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The German Society of Rheumatology approved new German guidelines for the sequential medical treatment of rheumatoid arthritis (RA) based on the European League Against Rheumatism (EULAR) recommendations for the management of RA published in 2010. An update of the EULAR systematic literature research was performed in Medline, Embase, and Cochrane databases. Meta-analyses, controlled trials, cohort studies, and registry data addressing traditional and biologic disease-modifying antirheumatic drugs, glucocorticoids, and treatment strategies published between January 2009 and August 2011 were included. Two reviewers independently evaluated and compared the additional data that had been published after the time limit set by the EULAR recommendations. A national guideline working group developed an adapted set of recommendations. The new German guidelines were accepted by vote using an informal Delphi approach. Twelve recommendations and the resulting updated treatment algorithm were developed and approved as a practical orientation for rheumatologists. These recommendations are based on a successive treatment with traditional and biologic disease-modifying drugs depending on the individual progress of the disease and distinct patient characteristics. The German guidelines have been developed on the basis of the internationally well-recognized EULAR recommendations. In addition, more recent evidence from a systematic literature research was considered. They have been developed and approved by a group of national experts aiming at guidance for rheumatologists to reach best medical practice.

Indexed as

AlgorithmsAntirheumatic AgentsArthritis, RheumatoidBiological ProductsConsensusCritical PathwaysDelphi TechniqueDrug Administration ScheduleDrug SubstitutionDrug Therapy, CombinationEvidence-Based MedicineGermanyHumansRheumatologyTime FactorsTreatment OutcomeAntirheumatic AgentsBiological Products

Identifiers

PMID23942828
OpenAlexW2006464848

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.