ArticleSurgery today2014
Positive peritoneal washing cytology is a potential risk factor for the recurrence of curatively resected colorectal cancer.
Article in Surgery today, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05740267 (Natural Orifice Specimen Extraction Surgery for Colorectal Cancer), which is not on this map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Natural Orifice Specimen Extraction Surgery for Colorectal Cancer (NOSE for CRC)
Who cites it
11 citing papers in PubMed.
- Impact of the number of colorectal cancer lymph node metastases on intraperitoneal lavage cytology: a multi-institutional, prospective, observational study.Surgery today · 2026Observational
- Lavage cytology diagnosed by immunostaining may be a poor prognostic factor in pathological stage III colorectal cancer.Annals of gastroenterological surgery · 2025Article
- Investigation of Peritoneal Lavage Cytology before and after Tumor Resection as a Prognostic Factor in Colorectal Cancer.Journal of the anus, rectum and colon · 2025Article
- Comparison of prognostic impact between positive intraoperative peritoneal and lavage cytologies in colorectal cancer.International journal of clinical oncology · 2021Article
- An Unusual Progression of Signet-Ring Cell Carcinoma of the Appendix in a Caucasian Woman.Journal of gastrointestinal cancer · 2019Article
- Metastatic Colorectal Cancer to the Peritoneum: Current Treatment Options.Current treatment options in oncology · 2018Review
- Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) delivered via a modified perfusion system for peritoneal carcinomatosis of colorectal origin.Surgery today · 2016Article
- Detection methods and clinical significance of free peritoneal tumor cells found during colorectal cancer surgery.World journal of gastrointestinal surgery · 2015Article
- Incidence and prognostic significance of positive peritoneal lavage in colorectal cancer.Surgery today · 2015Review
- Evaluation of the efficacy of peritoneal lavage with distilled water in colorectal cancer surgery: in vitro and in vivo study.Journal of gastroenterology · 2015Article
- Colorectal Cancer: Correlating the Role of Peritoneal Fluid Cytology to Tumor Biology and Stage: A Prospective Study from Pakistan.Euroasian journal of hepato-gastroenterologyArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposesWhether free peritoneal cancer cells should be considered peritoneal dissemination in colorectal cancer patients remains controversial. The aim of this study was to investigate the clinical significance of positive peritoneal washing cytology (PWC) in patients with colorectal cancer.
methodsWe retrospectively analyzed the records of 771 sequential patients diagnosed with stage 0-III colorectal cancer who underwent R0 resection and had no distant metastases or peritoneal dissemination.
resultsPWC was performed on all 771 patients. Sixty-eight patients experienced metastasis recurrence, 10 of whom experienced peritoneal recurrence. Of the 10 patients with peritoneal recurrence, 6 had positive PWC. Out of the 771 patients, 21 had positive PWC. Of these 21 patients, 6 had peritoneal recurrence, while 4 had distant metastasis and no peritoneal recurrence during the observation period. The 5-year disease-free survival was 89.0 % in the patients with negative PWC vs. 46.8 % in the patients with positive PWC (p < 0.0001, log-rank test). A Cox proportional hazards model revealed that positive PWC was the strongest independent risk factor for cancer-specific recurrence.
conclusionsOur study highlights PWC as a useful prognostic tool in patients undergoing curative surgery for colorectal cancer, since positive PWC was shown to be a potential risk factor for recurrence.
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