Evidence map›Paper›PMID 23942632›Full record

ArticleJournal of biomedical optics2013

Fast segmentation and high-quality three-dimensional volume mesh creation from medical images for diffuse optical tomography.

Michael Jermyn, Hamid Ghadyani, Michael A Mastanduno, Wes Turner, Scott C Davis, Hamid Dehghani, Brian W Pogue

Open access · hybridAbstract read
In one paragraph

Article in Journal of biomedical optics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed
15.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 190 citations in OpenAlex.

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38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Michael JermynDartmouth College, Thayer School of Engineering, Hanover, New Hampshire 03755, USA. michael.jermyn@dartmouth.edu
Hamid Ghadyani
Michael A Mastanduno
Wes Turner
Scott C Davis
Hamid Dehghani
Brian W Pogue
Dartmouth College · USKitware (United States) · US

Funding

Small Molecule Enhancers of Photodynamic Therapy for Skin CancerP01CA084203 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Bryan Quilty Spring · 2001 to 2026
$27.9M
NIRFASTR01CA132750 · NCI · DARTMOUTH COLLEGE · PI POGUE, BRIAN WILLIAM · 2009 to 2012
$1.2M
NCI NIH HHS P01 CA084203NCI NIH HHS P01 CA84203NCI NIH HHS R01 CA132750
6 · The paper itself

Abstract

Multimodal approaches that combine near-infrared (NIR) and conventional imaging modalities have been shown to improve optical parameter estimation dramatically and thus represent a prevailing trend in NIR imaging. These approaches typically involve applying anatomical templates from magnetic resonance imaging/computed tomography/ultrasound images to guide the recovery of optical parameters. However, merging these data sets using current technology requires multiple software packages, substantial expertise, significant time-commitment, and often results in unacceptably poor mesh quality for optical image reconstruction, a reality that represents a significant roadblock for translational research of multimodal NIR imaging. This work addresses these challenges directly by introducing automated digital imaging and communications in medicine image stack segmentation and a new one-click three-dimensional mesh generator optimized for multimodal NIR imaging, and combining these capabilities into a single software package (available for free download) with a streamlined workflow. Image processing time and mesh quality benchmarks were examined for four common multimodal NIR use-cases (breast, brain, pancreas, and small animal) and were compared to a commercial image processing package. Applying these tools resulted in a fivefold decrease in image processing time and 62% improvement in minimum mesh quality, in the absence of extra mesh postprocessing. These capabilities represent a significant step toward enabling translational multimodal NIR research for both expert and nonexpert users in an open-source platform.

Indexed as

SoftwareAlgorithmsImage EnhancementImage Interpretation, Computer-AssistedImaging, Three-DimensionalPattern Recognition, AutomatedReproducibility of ResultsSensitivity and SpecificitySpectroscopy, Near-InfraredTomography, Optical

Identifiers

PMID23942632
PMCPMC3739873
OpenAlexW2071404056

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.