ReviewAdvances in applied microbiology2013
Regulation of bacterial pathogenesis by intestinal short-chain Fatty acids.
Review in Advances in applied microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 159 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Vigiis 101-LAB on Gut Health
Functional Assessment in The Intestinal Flora Improvement
Who cites it
159 citing papers in PubMed, 3 syntheses or guidelines pooled it, 336 citations in OpenAlex.
- Systematic review of products with potential application for use in the control of Campylobacter spp. in organic and free-range broilers.Acta veterinaria Scandinavica · 2022Pooled it
- Microbiome Changes after Type 2 Diabetes Treatment: A Systematic Review.Medicina (Kaunas, Lithuania) · 2021Pooled it
- Meta-Analysis of Fecal Microbiota and Metabolites in Experimental Colitic Mice during the Inflammatory and Healing Phases.Nutrients · 2017Pooled it
- Association of Maternal Microbiota and Diet in Cord Blood Cytokine and Immunoglobulin Profiles.International journal of molecular sciences · 2021Trial
- Article
- Comprehensive profiling of antibiotic resistance genes and functional clusters of orthologous groups annotation of gut microbiota in Indonesian Kedu chickens.Journal, genetic engineering & biotechnology · 2026Article
- Environmental regulation of virulence in Vibrio cholerae: integrating multi-omics, predictive models, and comparative insights across emerging Vibrio species.Gut pathogens · 2026Review
- Article
- Nutritional strategies to mitigate sub-clinical coccidiosis in Eimeria-challenged broilers.Poultry science · 2026Article
- The regulatory effects of solid-state fermentedFood chemistry: X · 2026Article
- Capecitabine combined with fecal microbiota transplantation prevents colorectal cancer progression through correction of microbial dysbiosis and immune regulation.Scientific reports · 2026Article
- Impact of dietary replacement of soybean meal with high-protein wheat on gut microbial metabolism in chickens.Scientific reports · 2026Article
- In mouse and in vitro models, bowel preparation promotes pathogen colonization, translocation, and exacerbation of inflammation.Cell reports. Medicine · 2026Article
- Adaptive metabolic strategies of intracellular bacterial pathogens.Frontiers in microbiology · 2026Review
- Dietary energy levels regulate feed intake of broilers through the brain-gut axis.Frontiers in veterinary science · 2026Article
- Probiotics and iron bioavailability: mechanisms, clinical evidence, and translational applications-a comprehensive review of the probiotic strainFrontiers in nutrition · 2026Review
- Bibliometric Analysis of Gut Microbiota and Hepatocellular Carcinoma: Research Trends and Frontiers.Journal of hepatocellular carcinoma · 2026Article
- The Role of Probiotics in Enhancing Animal Health: Mechanisms, Benefits, and Applications in Livestock and Companion Animals.Animals : an open access journal from MDPI · 2025Review
- The emerging view on the roles of butyrate inInfection and immunity · 2025Review
- Identification of strain-specific cues that regulate biofilm formation inMicrobiology spectrum · 2025Article
99 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The human gut microbiota is inextricably linked to health and disease. One important function of the commensal organisms living in the intestine is to provide colonization resistance against invading enteric pathogens. Because of the complex nature of the interaction between the microbiota and its host, multiple mechanisms likely contribute to resistance. In this review, we dissect the biological role of short-chain fatty acids (SCFA), which are fermentation end products of the intestinal microbiota, in host-pathogen interactions. SCFA exert an extensive influence on host physiology through nutritional, regulatory, and immunomodulatory functions and can also affect bacterial fitness as a form of acid stress. Moreover, SCFA act as a signal for virulence gene regulation in common enteric pathogens. Taken together, these studies highlight the importance of the chemical environment where the biology of the host, the microbiota, and the pathogen intersects, which provides a basis for designing effective infection prevention and control.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.