Evidence map›Paper›PMID 23942059›Full record

Trial reportAIDS (London, England)2014

Home visits during pregnancy enhance male partner HIV counselling and testing in Kenya: a randomized clinical trial.

Alfred Onyango Osoti, Grace John-Stewart, James Kiarie, Barbra Richardson, John Kinuthia, Daisy Krakowiak, Carey Farquhar

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in AIDS (London, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 4 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alfred Onyango OsotiaDepartment of Obstetrics & Gynecology, AIC Kijabe Hospital, Kijabe, Kenya bDepartment of Epidemiology cDepartment of Global Health dDepartment of Medicine, University of Washington, Seattle, Washington, USA eDepartment of Obstetrics & Gynecology, University of Nairobi, Nairobi, Kenya fDepartment of Biostatistics, University of Washington, Seattle, Washington, USA gDepartment of Obstetrics & Gynecology, Kenyatta National Hospital, Nairobi, Kenya hVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Grace John-Stewart
James Kiarie
Barbra Richardson
John Kinuthia
Daisy Krakowiak
Carey Farquhar

Funding

INTERNATIONAL TRAINING GRANT IN EPIDEMIOLOGYD43TW000007 · FIC · UNIVERSITY OF WASHINGTON · PI FARQUHAR, CAREY · 1988 to 2012
$16.3M
Pediatric HIV-1 in Africa: Pathogenesis and ManagementK24HD054314 · NICHD · UNIVERSITY OF WASHINGTON · PI JOHN-STEWART, GRACE C. · 2006 to 2016
$1.2M
Gestational diabetes mellitus, gestational hypertension and risk of metabolic syndromeK43TW010363 · FIC · UNIVERSITY OF NAIROBI · PI OSOTI, ALFRED ONYANGO · 2016 to 2020
$566k
FIC NIH HHS D43 TW000007FIC NIH HHS K43 TW010363NICHD NIH HHS K24 HD054314
6 · The paper itself

Abstract

backgroundHIV testing male partners of pregnant women may decrease HIV transmission to women and promote uptake of prevention of mother-to-child HIV transmission (PMTCT) interventions. However, it has been difficult to access male partners in antenatal care (ANC) clinics. We hypothesized that home visits to offer HIV testing to partners of women attending ANC would increase partner HIV testing.

methodsWomen attending their first ANC were enrolled, interviewed using smartphone audio-computer-assisted self-interviews and randomized to home visits or written invitations for male partners to come to clinic, if they were married or cohabiting, unaccompanied by partners and had no prior couple HIV counselling and testing (CHCT). Enrolled men were offered CHCT (HIV testing and mutual disclosure). Prevalence of CHCT, male HIV seropositivity, couple serodiscordance and intimate partner violence, reported as physical threat from partner, were compared at 6 weeks.

resultsAmong 495 women screened, 312 were eligible, and 300 randomized to clinic-based or home-based CHCT. Median age was 22 years (interquartile range 20-26 years), and 87% were monogamous. CHCT was significantly higher in home-visit than in clinic-invitation arm (n = 128, 85% vs. n = 54, 36%; P < 0.001). Home-arm identified more HIV-seropositive men (12.0 vs. 8.0%; P = 0.248) and more HIV-discordant couples (14.7 vs. 4.7%; P = 0.003). There was no difference in intimate partner violence.

conclusionHome visits of pregnant women were safe and resulted in more male partner testing and mutual disclosure of HIV status. This strategy could facilitate prevention of maternal HIV acquisition, improve PMTCT uptake and increase male HIV diagnosis.

Indexed as

House CallsPregnant PeopleSexual PartnersAdultFemaleHIV InfectionsHumansInterviews as TopicKenyaMalePregnancyYoung Adult

Identifiers

PMID23942059
PMCPMC4337402

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.