ArticleBrain stimulation
Left cathodal trans-cranial direct current stimulation of the parietal cortex leads to an asymmetrical modulation of the vestibular-ocular reflex.
Article in Brain stimulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 47 citations in OpenAlex.
- Vestibular stimulation improves insight into illness in schizophrenia spectrum disorders.Psychiatry research · 2017Trial
- Vestibular rehabilitation therapy in combination with transcranial direct current stimulation (tDCS) for treatment of chronic vestibular dysfunction in the elderly: a double-blind randomized controlled trial.Brazilian journal of otorhinolaryngologyTrial
- Investigation of Variations in Brain Activity Associated with Dizziness and Head Position Alterations During Gait.Healthcare (Basel, Switzerland) · 2026Article
- Effects of Transcranial Direct Current Stimulation of the Posterior Parietal Cortex on Visual and Vestibular Function.NeuroSci · 2026Article
- Visuo-vestibular integration for self-motion: human cortical area V6 prefers forward and congruent stimuli.Experimental brain research · 2025Article
- Vestibular Agnosia: Toward a Better Understanding of Its Mechanisms.Audiology research · 2025Review
- Influence of high-definition transcranial direct current stimulation to the parietal cortex on postural control: a single-blind randomized crossover study.Frontiers in human neuroscience · 2025Article
- Neuroimaging evidence of visual-vestibular interaction accounting for perceptual mislocalization induced by head rotation.Neurophotonics · 2024Article
- Visuospatial orientation: Differential effects of head and body positions.Neuroscience letters · 2022Article
- Left parietal involvement in motion sickness susceptibility revealed by multimodal magnetic resonance imaging.Human brain mapping · 2022Article
- Article
- Multisensory contribution in visuospatial orientation: an interaction between neck and trunk proprioception.Experimental brain research · 2021Article
- Magnitude Estimates Orchestrate Hierarchal Construction of Context-Dependent Representational Maps for Vestibular Space and Time: Theoretical Implications for Functional Dizziness.Frontiers in integrative neuroscience · 2021Review
- Cathodal Transcranial Direct Current Stimulation Over the Right Temporoparietal Junction Suppresses Its Functional Connectivity and Reduces Contralateral Spatial and Temporal Perception.Frontiers in neuroscience · 2021Article
- Vestibulo-cortical hemispheric dominance: The link between anxiety and the vestibular system?The European journal of neuroscience · 2018Article
- Errors of Upright Perception in Patients With Vestibular Migraine.Frontiers in neurology · 2018Article
- Influence of biases in numerical magnitude allocation on human prosocial decision making.Journal of neurophysiology · 2017Article
- Functional neuroimaging of visuo-vestibular interaction.Brain structure & function · 2017Article
- Altered functional brain connectivity in patients with visually induced dizziness.NeuroImage. Clinical · 2017Article
- Bidirectional Modulation of Numerical Magnitude.Cerebral cortex (New York, N.Y. : 1991) · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Multi-sensory visuo-vestibular cortical areas within the parietal lobe are important for spatial orientation and possibly for descending modulation of the vestibular-ocular reflex (VOR). Functional imaging and lesion studies suggest that vestibular cortical processing is localized primarily in the non-dominant parietal lobe. However, the role of inter-hemispheric parietal balance in vestibular processing is poorly understood. Therefore, we tested whether experimentally induced asymmetries in right versus left parietal excitability would modulate vestibular function. VOR function was assessed in right-handed normal subjects during caloric ear irrigation (30 °C), before and after trans-cranial direct current stimulation (tDCS) was applied bilaterally over the parietal cortex. Bilateral tDCS with the anode over the right and the cathode over the left parietal region resulted in significant asymmetrical modulation of the VOR, with highly suppressed responses during the right caloric irrigation (i.e. rightward slow phase nystagmus). In contrast, we observed no VOR modulation during either cathodal stimulation of the right parietal cortex or SHAM tDCS conditions. Application of unilateral tDCS revealed that the left cathodal stimulation was critical in inducing the observed modulation of the VOR. We show that disruption of parietal inter-hemispheric balance can induce asymmetries in vestibular function. This is the first report using neuromodulation to show right hemisphere dominance for vestibular cortical processing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.