ArticleJournal of the American Chemical Society2013
Polymerization-induced self-assembly of galactose-functionalized biocompatible diblock copolymers for intracellular delivery.
Article in Journal of the American Chemical Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Galactose-Functional RAFT Agent for Biorelevant Polymeric Materials.ACS polymers Au · 2026Article
- Influence of the Saccharide Structure on Cargo Loading, Thermal Properties, and Lectin Binding of Amphiphilic Glycopolymer-Polylactic Acid Block Copolymer Nanoparticles.Bioconjugate chemistry · 2025Article
- Recent advances in permeable polymersomes: fabrication, responsiveness, and applications.Chemical science · 2023Review
- Polymersome-based protein drug delivery - quo vadis?Chemical Society reviews · 2023Review
- Polymerization-Induced Self-Assembly for Efficient Fabrication of Biomedical Nanoplatforms.Research (Washington, D.C.) · 2023Review
- Glycopolymer-Based Materials: Synthesis, Properties, and Biosensing Applications.Topics in current chemistry (Cham) · 2022Review
- Dextran-Coated Latex Nanoparticles via Photo-RAFT Mediated Polymerization Induced Self-Assembly.Polymers · 2021Article
- Construction of Highly Ordered Glyco-Inside Nano-Assemblies through RAFT Dispersion Polymerization of Galactose-Decorated Monomer.Angewandte Chemie (International ed. in English) · 2021Article
- Effects of Stereochemistry and Hydrogen Bonding on Glycopolymer-Amyloid-β Interactions.Biomacromolecules · 2020Article
- Characterizing the Core-Shell Architecture of Block Copolymer Nanoparticles with Electron Microscopy: A Multi-Technique Approach.Polymers · 2020Article
- Tailoring Polymersome Shape Using the Hofmeister Effect.Biomacromolecules · 2020Article
- A Single Thermoresponsive Diblock Copolymer Can Form Spheres, Worms or Vesicles in Aqueous Solution.Angewandte Chemie (International ed. in English) · 2019Article
- Nonequilibrium Reshaping of PolymersomesACS nano · 2019Article
- Tannic Acid-Mediated Aggregate Stabilization of Poly(Nanomaterials (Basel, Switzerland) · 2019Article
- Morphology-Variable Aggregates Prepared from Cholesterol-Containing Amphiphilic Glycopolymers: Their Protein Recognition/Adsorption and Drug Delivery Applications.Nanomaterials (Basel, Switzerland) · 2018Article
- Photoinitiated Polymerization-Induced Self-Assembly (Photo-PISA): New Insights and Opportunities.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2017Review
- Using Dynamic Covalent Chemistry To Drive Morphological Transitions: Controlled Release of Encapsulated Nanoparticles from Block Copolymer Vesicles.Journal of the American Chemical Society · 2017Article
- Nanotechnology in Glycomics: Applications in Diagnostics, Therapy, Imaging, and Separation Processes.Medicinal research reviews · 2017Review
- Preparation and Cross-Linking of All-Acrylamide Diblock Copolymer Nano-Objects via Polymerization-Induced Self-Assembly in Aqueous Solution.Macromolecules · 2017Article
- Photoresponsive Polymeric Reversible Nanoparticles via Self-Assembly of Reactive ABA Triblock Copolymers and Their Transformation to Permanent Nanostructures.Materials (Basel, Switzerland) · 2016Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent advances in polymer science are enabling substantial progress in nanobiotechnology, particularly in the design of new tools for enhanced understanding of cell biology and for smart drug delivery formulations. Herein, a range of novel galactosylated diblock copolymer nano-objects is prepared directly in concentrated aqueous solution via reversible addition-fragmentation chain transfer polymerization using polymerization-induced self-assembly. The resulting nanospheres, worm-like micelles, or vesicles interact in vitro with galectins as judged by a turbidity assay. In addition, galactosylated vesicles are highly biocompatible and allow intracellular delivery of an encapsulated molecular cargo.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.