ArticleMalaria journal2013
Plasmodium knowlesi and HIV co-infection in a German traveller to Thailand.
Article in Malaria journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Genetic Diversity, Haplotype Relationships, andTropical medicine and infectious disease · 2022Article
- Clinical management of Plasmodium knowlesi malaria.Advances in parasitology · 2021Review
- Malaria parasites in macaques in Thailand: stump-tailed macaques (Macaca arctoides) are new natural hosts for Plasmodium knowlesi, Plasmodium inui, Plasmodium coatneyi and Plasmodium fieldi.Malaria journal · 2020Article
- Association of Dengue Virus and Leptospira Co-Infections with Malaria Severity.Emerging infectious diseases · 2020Article
- Retrospective clinical case series study in 2017 identifiesEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2018Article
- Plasmodium knowlesi infection in a returning German traveller from Thailand: a case report on an emerging malaria pathogen in a popular low-risk travel destination.BMC infectious diseases · 2018Article
- Rapid-Antigen Test Negative Malaria in a Traveler Returning From Thailand, Molecularly Diagnosed as Plasmodium knowlesi.Open forum infectious diseases · 2016Article
- Plasmodium knowlesi as a Threat to Global Public Health.The Korean journal of parasitology · 2015Review
- Plasmodium knowlesi malaria: Overview Focussing on Travel-Associated Infections.Current infectious disease reports · 2015Article
- Severe Plasmodium knowlesi infection with multi-organ failure imported to Germany from Thailand/Myanmar.Malaria journal · 2014Article
- Molecular epidemiology of the emerging human malaria parasite "Plasmodium knowlesi".Tropical parasitology · 2014Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A case of Plasmodium knowlesi and HIV co-infection is reported in a German traveller returning from Thailand. The 54 year-old patient presented to the Institute of Tropical Medicine in Tübingen with a 11-day history of daily fever and chills. Initial microscopic evaluation of Giemsa-stained thin blood smears was suggestive of a mixed infection with Plasmodium falciparum and Plasmodium malariae. However, PCR amplification of small subunit ribosomal RNA gene revealed a P. knowlesi infection. Parasitaemia was 473 parasites/μl and the platelet count was within the normal range. Oral treatment with Malarone® was initiated and resulted in a fast recovery without any complications. As part of routine screening the patient also underwent HIV testing and was found to be HIV positive with a CD4 cell count of 115/μl and a viral load of 34,799 copies/ml. A follow-up measurement of the viral load seven days after the first quantification revealed an increase to 102,000 copies/ml. Three months after the first quantification the viral load had dropped to 10,000 copies/ml without the initiation of antiretroviral treatment. This suggests the possibility of a P. knowlesi malaria-induced temporary elevation of viral load similar to that reported for P. falciparum and HIV co-infection.
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