Evidence map›Paper›PMID 23940249›Full record

ArticlePediatrics2013

Factors associated with late detection of critical congenital heart disease in newborns.

April L Dawson, Cynthia H Cassell, Tiffany Riehle-Colarusso, Scott D Grosse, Jean Paul Tanner, Russell S Kirby, Sharon M Watkins, Jane A Correia, Richard S Olney

Abstract read
In one paragraph

Article in Pediatrics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Photoplethysmographic waveform characteristics of newborns with coarctation of the aorta.Journal of perinatology : official journal of the California Perinatal Association · 2017
    Article
  10. Review
  11. Observational
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

April L DawsonNational Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA, USA. isp3@cdc.gov
Cynthia H Cassell
Tiffany Riehle-Colarusso
Scott D Grosse
Jean Paul Tanner
Russell S Kirby
Sharon M Watkins
Jane A Correia
Richard S Olney
Centers for Disease Control and Prevention · USFlorida Department of Health · USNational Center on Birth Defects and Developmental Disabilities · USUniversity of South Florida · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

objectivesCritical congenital heart disease (CCHD) was recently added to the US Recommended Uniform Screening Panel for newborns. This study assessed whether maternal/household and infant characteristics were associated with late CCHD detection.

methodsThis was a statewide, population-based, retrospective, observational study of infants with CCHD born between 1998 and 2007 identified by using the Florida Birth Defects Registry. We examined 12 CCHD conditions that are primary and secondary targets of newborn CCHD screening using pulse oximetry. We used Poisson regression models to analyze associations between selected characteristics (eg, CCHD type, birth hospital nursery level [highest level available in the hospital]) and late CCHD detection (defined as diagnosis after the birth hospitalization).

resultsOf 3603 infants with CCHD and linked hospitalizations, CCHD was not detected during the birth hospitalization for 22.9% (n = 825) of infants. The likelihood of late detection varied by CCHD condition. Infants born in a birth hospital with a level I nursery only (adjusted prevalence ratio: 1.9 [95% confidence interval: 1.6-2.2]) or level II nursery (adjusted prevalence ratio: 1.5 [95% confidence interval: 1.3-1.7]) were significantly more likely to have late-detected CCHD compared with infants born in a birth hospital with a level III (highest) nursery.

conclusionsAfter controlling for the selected characteristics, hospital nursery level seems to have an independent association with late CCHD detection. Thus, perhaps universal newborn screening for CCHD could be particularly beneficial in level I and II nurseries and may reduce differences in the frequency of late diagnosis between birth hospital facilities.

Indexed as

Delayed DiagnosisNeonatal ScreeningAdultCross-Sectional StudiesDelivery RoomsFemaleFloridaHeart Defects, CongenitalHumansInfant, NewbornMalePatient DischargePoisson DistributionPregnancyRegression AnalysisRetrospective Studiescongenital heart diseaseneonatal screening

Identifiers

PMID23940249
PMCPMC4617641
OpenAlexW2100849619

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.