ArticleGenome biology and evolution2013
Palindromic genes in the linear mitochondrial genome of the nonphotosynthetic green alga Polytomella magna.
Article in Genome biology and evolution, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 25 citations in OpenAlex.
- A record-setting mitogenome in the holoparasitic plant Balanophora yakushimensis accompanied by exceptional loss of organellar DNA repair and recombination genes.BMC biology · 2025Article
- Structure of a mitochondrial ribosome with fragmented rRNA in complex with membrane-targeting elements.Nature communications · 2022Article
- Article
- Phylogenetic and functional diversity of aldehyde-alcohol dehydrogenases in microalgae.Plant molecular biology · 2021Article
- Interaction of N-acetyl-l-glutamate kinase with the PII signal transducer in the non-photosynthetic alga Polytomella parva: Co-evolution towards a hetero-oligomeric enzyme.The FEBS journal · 2020Article
- Comparative analysis ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2019Article
- Coding palindromes in mitochondrial genes of Nematomorpha.Nucleic acids research · 2019Article
- Multiple Independent Changes in Mitochondrial Genome Conformation in Chlamydomonadalean Algae.Genome biology and evolution · 2017Article
- Complete mitochondrial genome ofMitochondrial DNA. Part B, Resources · 2016Article
- Complete mitochondrial genome ofMitochondrial DNA. Part B, Resources · 2016Article
- Buying in to bioinformatics: an introduction to commercial sequence analysis software.Briefings in bioinformatics · 2015Article
- Massive and widespread organelle genomic expansion in the green algal genus Dunaliella.Genome biology and evolution · 2015Article
- A plastid without a genome: evidence from the nonphotosynthetic green algal genus Polytomella.Plant physiology · 2014Article
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Authors and funding
4 authors at 3 institutions in 1 country.
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Abstract
Organelle DNA is no stranger to palindromic repeats. But never has a mitochondrial or plastid genome been described in which every coding region is part of a distinct palindromic unit. While sequencing the mitochondrial DNA of the nonphotosynthetic green alga Polytomella magna, we uncovered precisely this type of genic arrangement. The P. magna mitochondrial genome is linear and made up entirely of palindromes, each containing 1-7 unique coding regions. Consequently, every gene in the genome is duplicated and in an inverted orientation relative to its partner. And when these palindromic genes are folded into putative stem-loops, their predicted translational start sites are often positioned in the apex of the loop. Gel electrophoresis results support the linear, 28-kb monomeric conformation of the P. magna mitochondrial genome. Analyses of other Polytomella taxa suggest that palindromic mitochondrial genes were present in the ancestor of the Polytomella lineage and lost or retained to various degrees in extant species. The possible origins and consequences of this bizarre genomic architecture are discussed.
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