ArticleThorax2014
Ethnic differences in respiratory impairment.
Article in Thorax, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Pooled it
- Evaluation of Pulmonary Fibrosis Outcomes by Race and Ethnicity in US Adults.JAMA network open · 2023Article
- Article
- A proposal of spirometry reference equations for Korean workers.Annals of occupational and environmental medicine · 2022Article
- Extended Investigation of Exposure to Respirable Synthetic Amorphous Silica Dust and Its Potential Impact on Non-malignant Respiratory Morbidity.Frontiers in public health · 2022Article
- Association Between Preserved Ratio Impaired Spirometry and Clinical Outcomes in US Adults.JAMA · 2021Article
- Ethnic Variance in Prevalence of COPD among Smokers in a Real World Setting.The open respiratory medicine journal · 2020Article
- Early-life exposure to humidifier disinfectant determines the prognosis of lung function in children.BMC pulmonary medicine · 2019Article
- Longitudinal Phenotypes and Mortality in Preserved Ratio Impaired Spirometry in the COPDGene Study.American journal of respiratory and critical care medicine · 2018Observational
- African-American race and mortality in interstitial lung disease: a multicentre propensity-matched analysis.The European respiratory journal · 2018Article
- Racial or Ethnic Health Disparities among Older Adults in Four Population Groups in South Africa.Annals of global health · 2018Article
- Spirometry, Static Lung Volumes, and Diffusing Capacity.Respiratory care · 2017Article
- Severe COPD cases from Korea, Poland, and USA have substantial differences in respiratory symptoms and other respiratory illnesses.International journal of chronic obstructive pulmonary disease · 2017Article
- Asthma-COPD overlap syndrome in the US: a prospective population-based analysis of patient-reported outcomes and health care utilization.International journal of chronic obstructive pulmonary disease · 2017Article
- Review
- Respiratory symptoms, spirometric respiratory impairment, and respiratory disease in middle-aged and older persons.Journal of the American Geriatrics Society · 2015Article
- The effect of applying ethnicity-specific spirometric reference equations to Asian migrant workers in Korea.Annals of occupational and environmental medicine · 2015Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
objectiveSpirometric Z scores by lambda-mu-sigma (LMS) rigorously account for age-related changes in lung function. Recently, the Global Lung Function Initiative (GLI) expanded LMS spirometric Z scores to multiple ethnicities. Hence, in aging populations, the GLI provides an opportunity to rigorously evaluate ethnic differences in respiratory impairment, including airflow limitation and restrictive pattern.
methodsUsing data from the Third National Health and Nutrition Examination Survey, including participants aged 40-80, we evaluated ethnic differences in GLI-defined respiratory impairment, including prevalence and associations with mortality and respiratory symptoms.
resultsAmong 3506 white Americans, 1860 African Americans and 1749 Mexican Americans, the prevalence of airflow limitation was 15.1% (13.9% to 16.4%), 12.4% (10.7% to 14.0%) and 8.2% (6.7% to 9.8%), and restrictive pattern was 5.6% (4.6% to 6.5%), 8.0% (6.9% to 9.0%) and 5.7% (4.5% to 6.9%), respectively. Airflow limitation was associated with mortality in white Americans, African Americans and Mexican Americans-adjusted HR (aHR) 1.66 (1.23 to 2.25), 1.60 (1.09 to 2.36) and 1.80 (1.17 to 2.76), respectively, but associated with respiratory symptoms only in white Americans-adjusted OR (aOR) 2.15 (1.70 to 2.73). Restrictive pattern was associated with mortality but only in white Americans and African Americans-aHR 2.56 (1.84 to 3.55) and 3.23 (2.06 to 5.05), and associated with respiratory symptoms but only in white Americans and Mexican Americans-aOR 2.16 (1.51 to 3.07) and 2.12 (1.45 to 3.08), respectively.
conclusionsIn an aging population, we found ethnic differences in GLI-defined respiratory impairment. In particular, African Americans had high rates of respiratory impairment that were associated with mortality but not respiratory symptoms.
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Registered trials
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