ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2013
Functional endogenous viral elements in the genome of the parasitoid wasp Cotesia congregata: insights into the evolutionary dynamics of bracoviruses.
Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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38 citing papers in PubMed, 74 citations in OpenAlex.
- Exploring the Determinants of Polydnavirus Chromosomal Integration Across Host-Parasitoid Wasp Systems.Genome biology and evolution · 2026Article
- The role of a viral symbiont in the thermal mismatch of host-parasitoid interactions.The Journal of experimental biology · 2026Article
- Parasitic castration by a viral protein tyrosine phosphatase targeting the host cell cycle checkpoint protein Rad9A.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Multi-omic approach to characterize the venom of the parasitic wasp Cotesia congregata (Hymenoptera: Braconidae).BMC genomics · 2025Article
- Transcriptional dynamics during Heliothis zea nudivirus 1 infection in an ovarian cell line fromThe Journal of general virology · 2025Article
- A PolydnavirusViruses · 2022Article
- Viral histones: pickpocket's prize or primordial progenitor?Epigenetics & chromatin · 2022Review
- The Complete Genome ofJournal of virology · 2022Article
- Genome-Wide Patterns of Bracovirus Chromosomal Integration into Multiple Host Tissues during Parasitism.Journal of virology · 2021Article
- Bracoviruses recruit host integrases for their integration into caterpillar's genome.PLoS genetics · 2021Article
- The Presence of Ancient Core Genes Reveals Endogenization from Diverse Viral Ancestors in Parasitoid Wasps.Genome biology and evolution · 2021Article
- MicroRNAs from Snellenius manilae bracovirus regulate innate and cellular immune responses of its host Spodoptera litura.Communications biology · 2021Article
- Shrinking of repeating unit length in leucine-rich repeats from double-stranded DNA viruses.Archives of virology · 2021Article
- Genomic architecture of endogenous ichnoviruses reveals distinct evolutionary pathways leading to virus domestication in parasitic wasps.BMC biology · 2020Article
- Detecting bracoviral orthologs distribution in five tsetse fly species and the housefly genomes.BMC research notes · 2020Article
- Whole Genome Sequence of the Parasitoid WaspG3 (Bethesda, Md.) · 2018Article
- Cotesia congregata Bracovirus Circles EncodingJournal of virology · 2018Article
- The Domestication of a Large DNA Virus by the Wasp Venturia canescens Involves Targeted Genome Reduction through Pseudogenization.Genome biology and evolution · 2018Article
- Unexpected invasion of miniature inverted-repeat transposable elements in viral genomes.Mobile DNA · 2018Article
- Persistent expression of Cotesia plutellae bracovirus genes in parasitized host, Plutella xylostella.PloS one · 2018Article
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Authors and funding
13 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bracoviruses represent the most complex endogenous viral elements (EVEs) described to date. Nudiviral genes have been hosted within parasitoid wasp genomes since approximately 100 Ma. They play a crucial role in the wasp life cycle as they produce bracovirus particles, which are injected into parasitized lepidopteran hosts during wasp oviposition. Bracovirus particles encapsidate multiple dsDNA circles encoding virulence genes. Their expression in parasitized caterpillars is essential for wasp parasitism success. Here, we report on the genomic organization of the proviral segments (i.e. master sequences used to produce the encapsidated dsDNA circles) present in the Cotesia congregata parasitoid wasp genome. The provirus is composed of a macrolocus, comprising two-thirds of the proviral segments and of seven dispersed loci, each containing one to three segments. Comparative genomic analyses with closely related species gave insights into the evolutionary dynamics of bracovirus genomes. Conserved synteny in the different wasp genomes showed the orthology of the proviral macrolocus across different species. The nudiviral gene odv-e66-like1 is conserved within the macrolocus, suggesting an ancient co-localization of the nudiviral genome and bracovirus proviral segments. By contrast, the evolution of proviral segments within the macrolocus has involved a series of lineage-specific duplications.
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