ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2013
Comprehensive analysis of endogenous bornavirus-like elements in eukaryote genomes.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 88 citations in OpenAlex.
- Data-Driven Virus Discovery with Virushunter and Virusgatherer.NAR genomics and bioinformatics · 2026Article
- Unveiling the RNA viral diversity in three organs of the Asian house shrew (Frontiers in microbiology · 2026Article
- Article
- IFN-γ-Based ELISpot as a New Tool to Detect Human Infections with Borna Disease Virus 1 (BoDV-1): A Pilot Study.Viruses · 2023Article
- Article
- The hidden diversity of ancient bornaviral sequences from X and P genes in vertebrate genomes.Virus evolution · 2023Article
- Article
- Review
- Endogenous Viral Elements in Shrew Genomes Provide Insights into Pestivirus Ancient History.Molecular biology and evolution · 2022Article
- The Borna Disease Virus 2 (BoDV-2) Nucleoprotein Is a Conspecific Protein That Enhances BoDV-1 RNA-Dependent RNA Polymerase Activity.Journal of virology · 2021Article
- 100-My history of bornavirus infections hidden in vertebrate genomes.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Optimal Expression of the Envelope Glycoprotein of Orthobornaviruses Determines the Production of Mature Virus Particles.Journal of virology · 2021Article
- Virus-like insertions with sequence signatures similar to those of endogenous nonretroviral RNA viruses in the human genome.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- RNA polymerase III and antiviral innate immune response.Transcription · 2021Review
- Identification of African swine fever virus-like elements in the soft tick genome provides insights into the virus' evolution.BMC biology · 2020Article
- Villains or heroes? The raison d'être of viruses.Clinical & translational immunology · 2020Review
- RNA Virus-Based Episomal Vector with a Fail-Safe Switch Facilitating Efficient Genetic Modification and Differentiation of iPSCs.Molecular therapy. Methods & clinical development · 2019Article
- Article
- Intranasal Borna Disease Virus (BoDV-1) Infection: Insights into Initial Steps and Potential Contagiosity.International journal of molecular sciences · 2019Article
- Development of an RNA Virus-Based Episomal Vector Capable of Switching Transgene Expression.Frontiers in microbiology · 2019Article
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Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bornaviruses are the only animal RNA viruses that establish a persistent infection in their host cell nucleus. Studies of bornaviruses have provided unique information about viral replication strategies and virus-host interactions. Although bornaviruses do not integrate into the host genome during their replication cycle, we and others have recently reported that there are DNA sequences derived from the mRNAs of ancient bornaviruses in the genomes of vertebrates, including humans, and these have been designated endogenous borna-like (EBL) elements. Therefore, bornaviruses have been interacting with their hosts as driving forces in the evolution of host genomes in a previously unexpected way. Studies of EBL elements have provided new models for virology, evolutionary biology and general cell biology. In this review, we summarize the data on EBL elements including what we have newly identified in eukaryotes genomes, and discuss the biological significance of EBL elements, with a focus on EBL nucleoprotein elements in mammalian genomes. Surprisingly, EBL elements were detected in the genomes of invertebrates, suggesting that the host range of bornaviruses may be much wider than previously thought. We also review our new data on non-retroviral integration of Borna disease virus.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.