SynthesisMedical care2013
Collaborative chronic care models for mental health conditions: cumulative meta-analysis and metaregression to guide future research and implementation.
Synthesis in Medical care, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02543840 (Hybrid Controlled Trial to Implement Collaborative Care in General Mental Health), which is not on this map. Cited by 68 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Hybrid Controlled Trial to Implement Collaborative Care in General Mental Health
Who cites it
68 citing papers in PubMed, 3 syntheses or guidelines pooled it, 132 citations in OpenAlex.
- A Systematic Review of Interventions That Integrate Perinatal Mental Health Care Into Routine Maternal Care in Low- and Middle-Income Countries.Frontiers in psychiatry · 2022Pooled it
- Key Components of Effective Pediatric Integrated Mental Health Care Models: A Systematic Review.JAMA pediatrics · 2020Pooled it
- Patients' online access to their electronic health records and linked online services: a systematic interpretative review.BMJ open · 2014Pooled it
- Effects of collaborative care on recognition and management of common mental disorders by general practitioners: a cluster-randomised trial in Norway.BMC primary care · 2026Trial
- A collaborative primary and mental health care model with psychologist and psychiatrist working in GP practices: process evaluation of the implementation, challenges, and sustainability.BMC health services research · 2025Trial
- Matching depression management to severity prognosis in primary care: results of the Target-D randomised controlled trial.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021Trial
- Comparative effectiveness of external vs blended facilitation on collaborative care model implementation in slow-implementer community practices.Health services research · 2020Trial
- External facilitators' perceptions of internal facilitation skills during implementation of collaborative care for mental health teams: a qualitative analysis informed by the i-PARIHS framework.BMC health services research · 2020Trial
- Trial
- A method to reduce imbalance for site-level randomized stepped wedge implementation trial designs.Implementation science : IS · 2019Trial
- Effectiveness of Implementing a Collaborative Chronic Care Model for Clinician Teams on Patient Outcomes and Health Status in Mental Health: A Randomized Clinical Trial.JAMA network open · 2019Trial
- Randomized Controlled Trial of a Collaborative Care Intervention for Mood Disorders by a National Commercial Health Plan.Psychiatric services (Washington, D.C.) · 2019Trial
- Collaborative Care for Depression and Posttraumatic Stress Disorder: Evaluation of Collaborative Care Fidelity on Symptom Trajectories and Outcomes.Journal of general internal medicine · 2018Trial
- Trial
- Clinical effectiveness of integrating depression care management into medicare home health: the Depression CAREPATH Randomized trial.JAMA internal medicine · 2015Trial
- Integrated care programmes for severe mental illnesses and comorbid physical health disorders: the EU-MIND umbrella review to inform future actions in Europe.EClinicalMedicine · 2026Review
- Implementing the collaborative chronic care model for mental health: a nonrandomized clinical trial.Implementation science communications · 2026Article
- First implementation of a collaborative care model for common mental disorders in primary care in France: fidelity of care manager intervention matters.BMC health services research · 2026Article
- Achieving cardiovascular health equity in community mental health: study protocol for a cluster-randomized hybrid Type 3 effectiveness-implementation trial.Implementation science : IS · 2025Article
- Caring Text Messages for Suicide Prevention in Urban American Indian Youth: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2025Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
objectivePrior meta-analysis indicates that collaborative chronic care models (CCMs) improve mental and physical health outcomes for individuals with mental disorders. This study aimed to investigate the stability of evidence over time and identify patient and intervention factors associated with CCM effects to facilitate implementation and sustainability of CCMs in clinical practice.
methodsWe reviewed 53 CCM trials that analyzed depression, mental quality of life (QOL), or physical QOL outcomes. Cumulative meta-analysis and metaregression were supplemented by descriptive investigations across and within trials.
resultsMost trials targeted depression in the primary care setting, and cumulative meta-analysis indicated that effect sizes favoring CCM quickly achieved significance for depression outcomes, and more recently achieved significance for mental and physical QOL. Four of 6 CCM elements (patient self-management support, clinical information systems, system redesign, and provider decision support) were common among reviewed trials, whereas 2 elements (health care organization support and linkages to community resources) were rare. No single CCM element was statistically associated with the success of the model. Similarly, metaregression did not identify specific factors associated with CCM effectiveness. Nonetheless, results within individual trials suggest that increased illness severity predicts CCM outcomes.
conclusionsSignificant CCM trials have been derived primarily from 4 original CCM elements. Nonetheless, implementing and sustaining this established model will require health care organization support. Although CCMs have typically been tested as population-based interventions, evidence supports stepped care application to more severely ill individuals. Future priorities include developing implementation strategies to support adoption and sustainability of the model in clinical settings while maximizing fit of this multicomponent framework to local contextual factors.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.