ArticleThe Neurohospitalist2012
A Neurologist's Guide to Acute Migraine Therapy in the Emergency Room.
Article in The Neurohospitalist, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02657031 (The Check Trial), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Check Trial: A Comparison of Headache Treatment in the ED: Compazine Versus Ketamine. A Multi-Center, Randomized Double-Blind, Clinical Control Trial.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Effectiveness of intravenous dexamethasone, metoclopramide, ketorolac, and chlorpromazine for pain relief and prevention of recurrence in the migraine headache: a prospective double-blind randomized clinical trial.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2019Trial
- Review
- Reduction of opioid and barbiturate use following initiation of rimegepant for migraine in the United States.Headache · 2026Article
- Opioid Use among People with Migraine: Results of the OVERCOME (US) Study.Pain and therapy · 2025Article
- Article
- Episodic Migraine in the Pediatric Population: Behavioral Therapies and other Non-Pharmacological Treatment Options.Current pain and headache reports · 2025Review
- A Retrospective Analysis of Disease Epidemiology, Comorbidity Burden, Treatment Patterns, and Healthcare Resource Utilization of Migraine in the United Arab Emirates.Pain and therapy · 2024Article
- Identifying therapeutic target genes for migraine by systematic druggable genome-wide Mendelian randomization.The journal of headache and pain · 2024Article
- Wildfire smoke exposure and emergency department visits for headache: A case-crossover analysis in California, 2006-2020.Headache · 2023Article
- Treating Vestibular Migraine When Pregnant and Postpartum: Progress, Challenges and Innovations.International journal of women's health · 2023Review
- Functionality, satisfaction, and global impression of change with ubrogepant for the acute treatment of migraine in triptan insufficient responders: a post hoc analysis of the ACHIEVE I and ACHIEVE II randomized trials.The journal of headache and pain · 2022Article
- Approach to Pediatric Intractable Migraine.Current neurology and neuroscience reports · 2021Review
- An Evaluation of Medication Prescribing Patterns for Acute Migraine in the Emergency Department: A Scoping Review.Journal of clinical medicine · 2021Article
- Acute Migraine Prescription Patterns Vary by Baseline Cardiovascular Risk and Clinical Characteristics: A Real-World Evidence Study.Pain and therapy · 2020Article
- Non-invasively triggered spreading depolarizations induce a rapid pro-inflammatory response in cerebral cortex.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020Article
- Acute headache management in emergency department. A narrative review.Internal and emergency medicine · 2020Review
- The need for new acutely acting antimigraine drugs: moving safely outside acute medication overuse.The journal of headache and pain · 2019Review
- Current Approach to Undifferentiated Headache Management in the Emergency Department.Current pain and headache reports · 2019Review
- Can we define migraine patients with blood high-sensitivity C-reactive protein and galectin-3 levels in the emergency department?Archives of medical science : AMS · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Migraine is a common reason for visits to the emergency room. Attacks that lead patients to come to the emergency room are often more severe, refractory to home rescue medication, and have been going on for longer. All of these features make these attacks more challenging to treat. The purpose of this article is to review available evidence pertinent to the treatment of acute migraine in adults in the emergency department setting in order to provide neurologists with a rational approach to management. Drug classes and agents reviewed include opioids, dopamine receptor antagonists, triptans, nonsteroidal anti-inflammatory drugs, corticosteroids, and sodium valproate.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.