ArticleInternational journal of clinical and experimental medicine2013
Lymphoplasmacyte-rich meningioma: our experience with 19 cases and a systematic literature review.
Article in International journal of clinical and experimental medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Epidemiology, characteristics, and prognostic factors of lymphoplasmacyte-rich meningioma: a systematic literature review.BMC cancer · 2024Pooled it
- Multinodular intraventricular lymphoplasmacyte-rich meningioma with significant calcification: a case description.Quantitative imaging in medicine and surgery · 2023Article
- Histopathology of Meningiomas.Advances in experimental medicine and biology · 2023Review
- Benign Spinal Tumors.Advances in experimental medicine and biology · 2023Article
- Angiomatous meningioma associated with rapidly aggravated peritumoral leptomeningitis: A case report.Surgical neurology international · 2023Article
- A case of Lymphoplasmacyte-rich meningioma mimicking pachymeningitis.BMC neurology · 2022Article
- Extradural Spinal Lymphoplasmacyte-Rich Meningioma in the Thoracic Spine: A Case Report and Literature Review.Journal of the Korean Society of Radiology · 2022Article
- Lymphoplasmacyte-rich meningioma: A rare histologic variant of benign meningioma with atypical bone invasion.Radiology case reports · 2022Article
- A rare lymphoplasmacyte-rich meningioma involving the dura of the skull base and cervical spinal cord: A case report.Translational neuroscience · 2022Article
- Lymphoplasmacyte-rich meningioma with hematologic signs and PD-L1 over-expression.Autopsy & case reports · 2022Article
- Lymphoplasmacyte-rich meningioma with atypical cystic-solid feature: A case report.World journal of clinical cases · 2020Article
- A rare cystic lymphoplasmacyte-rich meningioma: A case report and review of the literature.Surgical neurology international · 2020Article
- Large dural-based mass with bony hyperostosis in a 16-year-old male: IgG4-related disease mimicking lymphoplasmacyte-rich meningioma.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019Article
- Review
- Prognostic significance of preoperative neutrophilia on recurrence-free survival in meningioma.Neuro-oncology · 2017Article
- Prognostic significance of MYCN gene amplification and protein expression in primary brain tumors: Astrocytoma and meningioma.Cancer biomarkers : section A of Disease markers · 2017Article
- Immunohistochemical and genetic markers to distinguish hemangiopericytoma and meningioma.International journal of clinical and experimental medicine · 2015Article
- Pathology and molecular genetics of meningioma: recent advances.Neurologia medico-chirurgica · 2015Review
- IgG4 overexpression is rare in meningiomas with a prominent inflammatory component: a review of 16 cases.Brain pathology (Zurich, Switzerland) · 2014Article
- Minimal invasive trans-eyelid approach to anterior and middle skull base meningioma: a preliminary study of Shanghai Huashan hospital.International journal of clinical and experimental medicine · 2014Article
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Authors and funding
12 authors.
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Abstract
objectiveTo investigate the clinicopathological characteristics, prognosis, pathology, and differential diagnosis of LPM by analyzing our experience and reviewed relevant literature. We also postulated the necessity of postoperative adjuvant therapy.
methods19 patients with LPM underwent surgical treatment from 2007 through 2010 in our department. The clinical charts of the patients, including surgical, histological, and follow-up records, as well as imaging studies, were analyzed retrospectively. Other 43 cases searched from the literature were also included, so that 62 LPM cases were summarized and reviewed together.
resultsThe summarized 62 patients comprised 30 males and 31 females aged 9 years to 79 years (40.7±18.3 years). The most common locations were convexity, skull base, para-sagittal and cervical canal. Multiple or diffuse lesions were found in 8 cases. There were 13 patients had peripheral blood abnormalities (21%). One-third of the cases had moderate to severe peritumoral brain edema. Thirty-eight patients had total resection, 12 patients not specified while 12 received subtotal resection or only biopsy. MIB-1 was available in 24 cases and a third of them were higher than 3%. Follow-up more than 3 year was only completed in 19/62 cases. Seven cases suffered recurrence and two of them died after 2 years of operation.
conclusionLPM is a very rare benign variant of intracranial meningioma. Both lesions and hematological abnormalities have a predilection for younger individuals. Preoperative diagnosis of this subtype of meningioma is still difficult. Surgical resection is the primary treatment option, and supportive care for those not totally removed is very important, because the recurrence rate for this subtype is rather low. However, the massive infiltration of lymphocytes and plasma cells in LPMs are still controversial and the long-term follow-ups are needed. Radiotherapy is not recommended, and hormonal or immune-inhibitor therapy might be helpful.
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