ArticlePloS one2013
Bronchiectasis-associated hospitalizations in Germany, 2005-2011: a population-based study of disease burden and trends.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 6 of them syntheses that pooled it.
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Who cites it
67 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Management of Adult Bronchiectasis: Consensus-Based Guidelines of the German Respiratory Society.Respiration; international review of thoracic diseases · 2026Guideline
- Exercise training for bronchiectasis.The Cochrane database of systematic reviews · 2021Pooled it
- The economic burden of bronchiectasis - known and unknown: a systematic review.BMC pulmonary medicine · 2019Pooled it
- Positive expiratory pressure therapy versus other airway clearance techniques for bronchiectasis.The Cochrane database of systematic reviews · 2017Pooled it
- Effects of long-term use of macrolides in patients with non-cystic fibrosis bronchiectasis: a meta-analysis of randomized controlled trials.BMC infectious diseases · 2015Pooled it
- Macrolide therapy in adults and children with non-cystic fibrosis bronchiectasis: a systematic review and meta-analysis.PloS one · 2014Pooled it
- Effect of N-acetylcysteine on exacerbations of bronchiectasis (BENE): a randomized controlled trial.Respiratory research · 2019Trial
- The short and long term effects of exercise training in non-cystic fibrosis bronchiectasis--a randomised controlled trial.Respiratory research · 2014Trial
- Characteristics of Patients with Idiopathic Bronchiectasis in Comparison to Post-infectious Bronchiectasis in South Korea.Tuberculosis and respiratory diseases · 2026Article
- Genomic diversity and adaptive resistance mechanisms inmSystems · 2026Article
- Validation of Bronchiectasis Health Questionnaire (BHQ) in Chinese Patients With Noncystic Fibrosis Bronchiectasis.Canadian respiratory journal · 2026Article
- Evaluating serum TNF α in relation to bronchiectasis severity: Insights from FACED and BSI scoring systems.Lung India : official organ of Indian Chest Society · 2026Article
- Advanced Lung Cancer Inflammation Index (ALI) as an Independent Predictor for Bronchiectasis Exacerbation Risks.Journal of inflammation research · 2026Article
- Associations between leisure sedentary behaviors, physical activity, and chronic respiratory diseases: a Mendelian randomization study.Archives of medical science : AMS · 2025Article
- Bronchiectasis Exacerbation Increases the Risk of Adverse Renal Outcomes-Results From a Large Territory-Wide Cohort Study.The clinical respiratory journal · 2025Article
- Medical Causes of Hospitalisation among Patients with Bronchiectasis: A Nationwide Study in Japan.Pathogens (Basel, Switzerland) · 2024Article
- Systemic immune-inflammation index in predicting hospitalized bronchiectasis exacerbation risks and disease severity.Journal of thoracic disease · 2024Article
- Phenotype and Clinicoradiological Differences in Multifocal and Focal Bronchiectasis.Medicina (Kaunas, Lithuania) · 2024Article
- High-sensitivity C-reactive protein level in stable-state bronchiectasis predicts exacerbation risk.BMC pulmonary medicine · 2024Article
- Baseline neutrophil-to-lymphocyte ratio as a predictor of response to hospitalized bronchiectasis exacerbation risks.European clinical respiratory journal · 2024Article
7 more citing papers are in PubMed but not listed here.
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Abstract
backgroundRepresentative population-based data on the epidemiology of bronchiectasis in Europe are limited. The aim of the present study was to investigate the current burden and the trends of bronchiectasis-associated hospitalizations and associated conditions in Germany in order to inform focused patient care and to facilitate the allocation of healthcare resources.
methodsThe nationwide diagnosis-related groups hospital statistics for the years 2005-2011 were used in order to identify hospitalizations with bronchiectasis as any hospital discharge diagnosis according to the International Classification of Diseases, 10th revision, code J47, (acquired) bronchiectasis. Poisson log-linear regression analysis was used to assess the significance of trends. In addition, the overall length of hospital stay (LOS) and the in-hospital mortality in comparison to the nationwide overall mortality due to bronchiectasis as the primary diagnosis was assessed.
resultsOverall, 61,838 records with bronchiectasis were extracted from more than 125 million hospitalizations. The average annual age-adjusted rate for bronchiectasis as any diagnosis was 9.4 hospitalizations per 100,000 population. Hospitalization rates increased significantly during the study period, with the highest rate of 39.4 hospitalizations per 100,000 population among men aged 75-84 years and the most pronounced average annual increases among females. Besides numerous bronchiectasis-associated conditions, chronic obstructive pulmonary disease (COPD) was most frequently found in up to 39.2% of hospitalizations with bronchiectasis as the primary diagnosis. The mean LOS was comparable to that for COPD. Overall, only 40% of bronchiectasis-associated deaths occurred inside the hospital.
conclusionsThe present study provides evidence of a changing epidemiology and a steadily increasing prevalence of bronchiectasis-associated hospitalizations. Moreover, it confirms the diversity of bronchiectasis-associated conditions and the possible association between bronchiectasis and COPD. As the major burden of disease may be managed out-of-hospital, prospective patient registries are needed to establish the exact prevalence of bronchiectasis according to the specific underlying condition.
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