ArticlePloS one2013
Quantitative evaluation of contrast-enhanced ultrasonography in the diagnosis of chronic ischemic renal disease in a dog model.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 39 citations in OpenAlex.
- Assessment of pharmacologically induced changes in canine kidney function by multiparametric magnetic resonance imaging and contrast enhanced ultrasound.Frontiers in veterinary science · 2024Article
- Non-viral nitric oxide-based gene therapy improves perfusion and liposomal doxorubicin sonopermeation in neuroblastoma models.Theranostics · 2023Article
- Intra- and Inter-Observer Variability of Quantitative Parameters Used in Contrast-Enhanced Ultrasound of Kidneys of Healthy Cats.Animals : an open access journal from MDPI · 2022Article
- Evaluation of Renal Blood Flow in Dogs during Short-Term Human-Dose Epoprostenol Administration Using Pulsed Doppler and Contrast-Enhanced Ultrasonography.Animals : an open access journal from MDPI · 2022Article
- Ultrasonographic assessment of renal perfusion in bitches with mammary carcinoma treated with long-term carprofen.Scientific reports · 2021Article
- Impact of region-of-interest size and location on quantitative contrast-enhanced ultrasound of canine splenic perfusion.BMC veterinary research · 2021Article
- Clinical and ultrasound variables for early diagnosis of septic acute kidney injury in bitches with pyometra.Scientific reports · 2020Article
- Contrast-Enhanced Ultrasound Examination for the Assessment of Renal Perfusion in Cats with Chronic Kidney Disease.Journal of veterinary internal medicine · 2018Article
- New Ultrasound Techniques Promise Further Advances in AKI and CKD.Journal of the American Society of Nephrology : JASN · 2017Review
- Evaluation of Renal Perfusion in Hyperthyroid Cats before and after Radioiodine Treatment.Journal of veterinary internal medicine · 2017Article
- A Pilot Clinical Study in Characterization of Malignant Renal-cell Carcinoma Subtype with Contrast-enhanced Ultrasound.Ultrasonic imaging · 2017Article
- Contrast-enhanced ultrasound: A promising method for renal microvascular perfusion evaluation.Journal of translational internal medicine · 2016Review
- Contrast enhanced ultrasonography of kidney in conscious and anesthetized beagle dogs.The Journal of veterinary medical science · 2016Article
- Evaluation of Feline Renal Perfusion with Contrast-Enhanced Ultrasonography and Scintigraphy.PloS one · 2016Article
- Contrast-enhanced ultrasound of both kidneys in healthy, non-anaesthetized cats.Acta veterinaria Scandinavica · 2015Article
- Contrast-enhanced ultrasonography to assess blood perfusion of skeletal muscles in normal dogs.The Journal of veterinary medical science · 2015Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this feasibility study was to prospectively explore in a dog model of chronic ischemic renal disease (CIRD) the hypothesis that real-time contrast-enhanced ultrasonography (CEUS) can quantitatively evaluate the early perfusion changes of renal cortex. MATERIALS AND
methodsIn this animal care and use committee-approved study, the model of CIRD was carried out in healthy dogs (10.0~12.0 kg, n=5), by placing the Ameroid ring constrictors on the distal portion of right renal artery through operation. CEUS monitoring of right kidney perfusion was performed by intravenous bolus injection of 0.6 ml Sulfur hexafluoride filled microbubbles (SonoVue; Bracco S.P.A., Milan, Italy) every week after operation. The slope rate of ascending curve (A) and descending curve (α), area under curve (AUC), derived peak intensity (DPI), and time to peak (TTP) were measured in renal cortex using commercial quantification software (Q-LAB version 6; Philips Medical Systems, Bothell,WA,USA). The sensitivity of CEUS was compared with blood serum urea nitrogen (BUN) and serum creatinine (SCr) level.
resultsWith the progression of CIRD, dogs showed delayed enhancement and perfusion in renal CEUS curve. Earliest significant changes happened 4 weeks after operation on DPI and TTP which changed from 13.04 ± 2.71 to 15.58 ± 4.75 dB and 9.03 ± 2.01 to 10.62 ± 6.04 sec, respectively (P<.05).
conclusionsCEUS can display the perfusion changes of CIRD in the early period.
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