Evidence map›Paper›PMID 23936374›Full record

ArticlePloS one2013

Sex role segregation and mixing among men who have sex with men: implications for biomedical HIV prevention interventions.

Benjamin Armbruster, Sourya Roy, Abhinav Kapur, John A Schneider

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Benjamin ArmbrusterDepartment of Industrial Engineering and Management Sciences, Northwestern University, Evanston, Illinois, USA.
Sourya Roy
Abhinav Kapur
John A Schneider
Northwestern University · USUniversity of Chicago · US

Funding

Modeling MRSA in the CommunityU01GM087729 · NIGMS · UNIVERSITY OF CHICAGO · PI LAUDERDALE, DIANE SPERLING, MACAL, CHARLES MARTIN · 2009 to 2013
$3.6M
Social network positional selection of peer change agentsR21AI098599 · NIAID · UNIVERSITY OF CHICAGO · PI SCHNEIDER, JOHN · 2013 to 2014
$438k
Hybridized cell phone and survey generated communication networkR21HD068352 · NICHD · UNIVERSITY OF CHICAGO · PI SCHNEIDER, JOHN · 2012 to 2013
$387k
NIAID NIH HHS R21 AI098599NIAID NIH HHS R21AI098599NICHD NIH HHS HD068352NICHD NIH HHS R21 HD068352NIGMS NIH HHS U01 GM087729NIGMS NIH HHS U01 GM087729-01
6 · The paper itself

Abstract

objectiveMen who have sex with men (MSM) practice role segregation - insertive or receptive only sex positions instead of a versatile role - in several international settings where candidate biomedical HIV prevention interventions (e.g., circumcision, anal microbicide) will be tested. The effects of these position-specific interventions on HIV incidence are modeled. MATERIALS AND

methodsWe developed a deterministic compartmental model to predict HIV incidence among Indian MSM using data from 2003-2010. The model's sex mixing matrix was derived from network data of Indian MSM (n=4604). Our model captures changing distribution of sex roles over time. We modeled microbicide and circumcision efficacy on trials with heterosexuals.

resultsIncreasing numbers of versatile MSM resulted in little change in HIV incidence over 20 years. Anal microbicides and circumcision would decrease the HIV prevalence at 10 years from 15.6% to 12.9% and 12.7% respectively. Anal microbicides would provide similar protection to circumcision at the population level despite lower modeled efficacy (54% and 60% risk reduction, respectively). Combination of the interventions were additive: in 5 years, the reduction in HIV prevalence of the combination (-3.2%) is almost the sum of their individual reductions in HIV prevalence (-1.8% and -1.7%).

conclusionsMSM sex role segregation and mixing, unlike changes in the sex role distribution, may be important for evaluating HIV prevention interventions in international settings. Synergies between some position-specific prevention interventions such as circumcision and anal microbicides warrant further study.

Indexed as

Communicable Disease ControlGender IdentityAdultHIV InfectionsHomosexuality, MaleHumansMaleMiddle AgedModels, StatisticalResidence CharacteristicsYoung Adult

Identifiers

PMID23936374
PMCPMC3731341
OpenAlexW2033616394

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.