ArticleEvidence-based complementary and alternative medicine : eCAM2013
A review of the phytochemistry and pharmacological activities of raphani semen.
Article in Evidence-based complementary and alternative medicine : eCAM, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 66 citations in OpenAlex.
- Raphani Semen Extract Targets theFood science & nutrition · 2026Article
- Effect of modified Zengye decoction on age-related constipationGastroenterology report · 2026Article
- Protective Effect ofAntioxidants (Basel, Switzerland) · 2026Article
- The Effect of Light on the Germination ofGels (Basel, Switzerland) · 2025Article
- Pharmacological modulation of mitochondrial function as novel strategies for treating intestinal inflammatory diseases and colorectal cancer.Journal of pharmaceutical analysis · 2025Review
- Enhancing stability and bioavailability of sulforaphene in radish seed extracts using nanoemulsion made with high oleic sunflower oil.Food science and biotechnology · 2023Article
- Anti-Toxoplasma Activities of Some Egyptian Plant Extracts: An In Vitro Study.Acta parasitologica · 2022Article
- Robust Antiviral Activity of Santonica Flower Extract (ACS omega · 2022Article
- Evaluation of the Effects of Processing Technique on Chemical Components in Raphani Semen by HPLC and UPLC-Q-TOF-MS.International journal of analytical chemistry · 2022Article
- Raphani Semen (Nutrients · 2021Article
- Secondary Metabolites of Plants as Modulators of Endothelium Functions.International journal of molecular sciences · 2021Review
- Sinigrin Enhanced Antiasthmatic Effects of Beta Adrenergic Receptors Agonists by Regulating cAMP-Mediated Pathways.Frontiers in pharmacology · 2020Article
- Antidiabetic Potential of Medicinal Plants and Their Active Components.Biomolecules · 2019Review
- Dissection of the molecular targets and signaling pathways of Guzhi Zengsheng Zhitongwan based on the analysis of serum proteomics.Chinese medicine · 2019Article
- Radish (Raphanus sativus) and Diabetes.Nutrients · 2017Review
- Pharmacognostic outlooks on medical herbs of Sasang typology.Integrative medicine research · 2017Review
- BEHAVIORAL EVIDENCE OF ANTIDEPRESSANT-LIKE ACTIVITY OFAfrican journal of traditional, complementary, and alternative medicines : AJTCAM · 2017Article
- HOX-7 suppresses body weight gain and adipogenesis-related gene expression in high-fat-diet-induced obese mice.BMC complementary and alternative medicine · 2014Article
- Are famine food plants also ethnomedicinal plants? An ethnomedicinal appraisal of famine food plants of two districts of bangladesh.Evidence-based complementary and alternative medicine : eCAM · 2014Article
- Synergistic Effects of Natural Product Combinations in Protecting the Endothelium Against Cardiovascular Risk Factors.Journal of evidence-based integrative medicineReview
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The dried ripe seed of Raphanus sativus L., commonly known as radish seed (or Raphani Semen), is used as traditional Chinese medicine (TCM) to treat constipation, chronic tracheitis, and hypertension. The major active compounds in Raphani Semen are alkaloids, glucosinolates, brassinosteroids, and flavonoids. Fatty acids are its main nutritional contents. Raphani Semen has been demonstrated to have beneficial effects on hypertension, obesity, diabetes mellitus, constipation, and cough. So far, there is no report about the adverse/toxic effects of this herb on humans. However, Raphani Semen processed by roasting was reported to exhibit some adverse effects on mice. Additionally, erucic acid, the main fatty acid in Raphani Semen, was shown to enhance the toxicity of doxorubicin. Thus, Raphani Semen has a potential risk of causing toxicity and drug interaction. In summary, Raphani Semen is a valuable TCM herb with multiple pharmacological effects. More studies on Raphani Semen could help better understand its pharmacological mechanisms so as to provide clear scientific evidence to explain its traditional uses, to identify its therapeutic potential on other diseases, and to understand its possible harmful effects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.