ArticleEvidence-based complementary and alternative medicine : eCAM2013
"Intensity-response" effects of electroacupuncture on gastric motility and its underlying peripheral neural mechanism.
Article in Evidence-based complementary and alternative medicine : eCAM, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 29 citations in OpenAlex.
- Cutaneous TRPV4 Potentiates the Afferent Transmission of Electroacupuncture Stimulation.ACS omega · 2026Article
- Electroacupuncture alleviates depression and gastrointestinal dysfunction by rebalancing GABAergic activity in the central amygdala.World journal of psychiatry · 2026Article
- Electroacupuncture of ST36 and PC6 for postoperative gastrointestinal recovery: A systematic review and meta-analysis.Journal of traditional and complementary medicine · 2024Article
- Effects and mechanisms of acupuncture on women related health.Frontiers of medicine · 2024Review
- Acceleration of postoperative recovery with brief intraoperative vagal nerve stimulation mediatedFrontiers in neuroscience · 2023Article
- Fundamental Neurocircuit of Anti-inflammatory Effect by Electroacupuncture Stimulation Identified.Neuroscience bulletin · 2022Article
- Electroacupuncture enhances resting-state functional connectivity between dorsal caudate and precuneus and decreases associated leptin levels in overweight/obese subjects.Brain imaging and behavior · 2022Article
- Efficacy and Safety of Transcutaneous Electrical Acupoint Stimulation (TEAS) for Postoperative Pain in Laparoscopy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Evidence-based complementary and alternative medicine : eCAM · 2022Review
- Somato-Autonomic Reflexes of Acupuncture.Medical acupuncture · 2020Review
- Neuromechanism of acupuncture regulating gastrointestinal motility.World journal of gastroenterology · 2020Review
- Ameliorating Effects of Electroacupuncture on Dysmotility, Inflammation, and Pain Mediated via the Autonomic Mechanism in a Rat Model of Postoperative Ileus.Journal of neurogastroenterology and motility · 2019Article
- Electroacupuncture at ST36 Protects ICC Networks via mSCF/Kit-ETV1 Signaling in the Stomach of Diabetic Mice.Evidence-based complementary and alternative medicine : eCAM · 2017Article
- Somato stimulation and acupuncture therapy.Chinese journal of integrative medicine · 2016Review
- Electroacupuncture at ST25 inhibits jejunal motility: Role of sympathetic pathways and TRPV1.World journal of gastroenterology · 2016Article
- Electroacupuncture at ST37 Enhances Jejunal Motility via Excitation of the Parasympathetic System in Rats and Mice.Evidence-based complementary and alternative medicine : eCAM · 2016Article
- Electroacupuncture at ST25 Inhibits Cisapride-Induced Gastric Motility in an Intensity-Dependent Manner.Evidence-based complementary and alternative medicine : eCAM · 2016Article
- Treatment of Diabetic Gastroparesis by Complementary and Alternative Medicines.Medicines (Basel, Switzerland) · 2015Review
- Acupuncture and regulation of gastrointestinal function.World journal of gastroenterology · 2015Review
- Effects of Different Local Moxibustion-Like Stimuli at Zusanli (ST36) and Zhongwan (CV12) on Gastric Motility and Its Underlying Receptor Mechanism.Evidence-based complementary and alternative medicine : eCAM · 2015Article
- Somatosensory Nerve Fibers Mediated Generation of De-qi in Manual Acupuncture and Local Moxibustion-Like Stimuli-Modulated Gastric Motility in Rats.Evidence-based complementary and alternative medicine : eCAM · 2014Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to explore the "intensity-response" relationship between EAS and the effect of gastric motility of rats and its underlying peripheral neural mechanism by employing ASIC3 knockout (ASIC3-/-), TRPV1 knockout (TRPV1-/-), and C57BL/6 mice. For adult male Sprague-Dawley (n = 18) rats, the intensities of EAS were 0.5, 1, 3, 5, 7, and 9 mA, respectively. For mice (n = 8 in each group), only 1 mA was used, by which C fiber of the mice can be activated. Gastric antrum motility was measured by intrapyloric balloon. Gastric motility was facilitated by EAS at ST36 and inhibited by EAS at CV12. The half maximal facilitation intensity of EAS at ST36 was 2.1-2.3 mA, and the half maximal inhibitory intensity of EAS at CV12 was 2.8 mA. In comparison with C57BL/6 mice, the facilitatory effect of ST36 and inhibitive effect of CV12 in ASIC3-/- mice decreased, but the difference was not statistically significant (P > 0.05). However, these effects in TRPV1-/- mice decreased significantly (P < 0.001). The results indicated that there existed an "intensity-response" relationship between EAS and the effect of gastric motility. TRPV1 receptor was involved in the regulation of gastric motility of EAS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.