Evidence map›Paper›PMID 23935613›Full record

ArticleInterdisciplinary perspectives on infectious diseases2013

Entry, Retention, and Virological Suppression in an HIV Cohort Study in India: Description of the Cascade of Care and Implications for Reducing HIV-Related Mortality in Low- and Middle-Income Countries.

Gerardo Alvarez-Uria, Raghavakalyan Pakam, Manoranjan Midde, Praveen Kumar Naik

Registry-linked trialAbstract read
In one paragraph

Article in Interdisciplinary perspectives on infectious diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02454569 (Vicente Ferrer HIV Cohort Study), which is not on this map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02454569 recruitingnot on this map

Vicente Ferrer HIV Cohort Study

Typeobservational_patient_registrySponsorRural Development Trust HospitalRan2009 to 2040Enrolled30,000ConditionsHIV, Tuberculosis, Cryptococcosis, Opportunistic Infections
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. HIV care continuum among men who have sex with men and persons who inject drugs in India: barriers to successful engagement.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2015
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  10. Safety and tolerability of intrathecal liposomal amphotericinTherapeutic advances in infectious disease · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gerardo Alvarez-UriaDepartment of Infectious Diseases, Rural Development Trust Hospital, Kadiri Road, Bathalapalli, Anantapur District, Andhra Pradesh 515661, India.
Raghavakalyan Pakam
Manoranjan Midde
Praveen Kumar Naik

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HIV treatment, care, and support programmes in low- and middle-income countries have traditionally focused more on patients remaining in care after the initiation of antiretroviral therapy (ART) than on earlier stages of care. This study describes the cumulative retention from HIV diagnosis to the achievement of virological suppression after ART initiation in an HIV cohort study in India. Of all patients diagnosed with HIV, 70% entered into care within three months. 65% of patients ineligible for ART at the first assessment were retained in pre-ART care. 67% of those eligible for ART initiated treatment within three months. 30% of patients who initiated ART died or were lost to followup, and 82% achieved virological suppression in the last viral load determination. Most attrition occurred the in pre-ART stages of care, and it was estimated that only 31% of patients diagnosed with HIV engaged in care and achieved virological suppression after ART initiation. The total mortality attributable to pre-ART attrition was considerably higher than the mortality for not achieving virological suppression. This study indicates that early entry into pre-ART care along with timely initiation of ART is more likely to reduce HIV-related mortality compared to achieving virological suppression.

Identifiers

PMID23935613
PMCPMC3723357

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.