ArticleMikrochimica acta2012
Nanoporous gold as a solid support for protein immobilization and development of an electrochemical immunoassay for prostate specific antigen and carcinoembryonic antigen.
Article in Mikrochimica acta, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 35 citations in OpenAlex.
- Progress in Electrochemical Immunosensors with Alkaline Phosphatase as the Signal Label.Biosensors · 2023Review
- Facile fabrication of hierarchically nanostructured gold electrode for bio-electrochemical applications.Journal of electroanalytical chemistry (Lausanne, Switzerland) · 2022Article
- Anomalous Trends in Nucleic Acid-Based Electrochemical Biosensors with Nanoporous Gold Electrodes.Analytical chemistry · 2019Article
- Preparation, Modification, Characterization, and Biosensing Application of Nanoporous Gold Using Electrochemical Techniques.Nanomaterials (Basel, Switzerland) · 2018Review
- Nanomaterial-based biosensors for detection of prostate specific antigen.Mikrochimica acta · 2017Review
- Enzyme Immobilization on Nanoporous Gold: A Review.Biochemistry insights · 2017Review
- Prostate Cancer Stem Cells and Nanotechnology: A Focus on Wnt Signaling.Frontiers in pharmacology · 2017Review
- Electrochemical impedance spectroscopy study of carbohydrate-terminated alkanethiol monolayers on nanoporous gold: Implications for pore wetting.Journal of electroanalytical chemistry (Lausanne, Switzerland) · 2016Article
- Screen-printed electrode produced by printed-circuit board technology. Application to Cancer Biomarker Detection by means of plastic antibody as sensing material.Sensors and actuators. B, Chemical · 2016Article
- Selective capture of glycoproteins using lectin-modified nanoporous gold monolith.Journal of chromatography. A · 2015Article
- Diagnosis of prostate cancer via nanotechnological approach.International journal of nanomedicine · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Nanoporous gold (NPG) was utilized as a support for immobilizing alkaline phosphatase (ALP) conjugated to monoclonal antibodies against either prostate specific antigen (PSA) or carcinoembryonic antigen (CEA). The antibody-ALP conjugates were coupled to self-assembled monolayers of lipoic acid and used in direct kinetic assays. Using the enzyme substrate p-aminophenylphosphate, the product p-aminophenol was detected by its oxidation near 0.1 V (vs. Ag|AgCl) using square wave voltammetry. The difference in peak current arising from oxidation of p-aminophenol before and after incubation with biomarker increased with biomarker concentration. The response to these two biomarkers was linear up to 10 ng mL
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.