ArticleCirculation2013
Four-factor prothrombin complex concentrate for urgent reversal of vitamin K antagonists in patients with major bleeding.
Article in Circulation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Severe Hemoperitoneum From a Ruptured Ovarian Cyst in a Patient with Antiphospholipid Syndrome and Antithrombin III Deficiency: A Case Report.The American journal of case reports · 2025Article
- Correcting Coagulopathy for Image-Guided Procedures.Seminars in interventional radiology · 2022Review
- Management of Coagulopathy in Bleeding Patients.Journal of clinical medicine · 2021Review
- Factors contributing to poor outcome in patients on warfarin receiving 4-factor prothrombin complex concentrate in critically ill.Acta bio-medica : Atenei Parmensis · 2021Article
- Pharmacometric modeling to explore 4F-PCC dosing strategies for VKA reversal in patients with INR below 2.Blood advances · 2020Article
- An engineered factor Va prevents bleeding induced by direct-acting oral anticoagulants by different mechanisms.Blood advances · 2020Article
- The European guideline on management of major bleeding and coagulopathy following trauma: fifth edition.Critical care (London, England) · 2019Article
- Approaches to prevent bleeding associated with anticoagulants: current status and recent developments.Drug delivery and translational research · 2018Review
- Dabigatran etexilate: appropriate use in patients with chronic kidney disease and in the elderly patients.Internal and emergency medicine · 2017Review
- Clinical effectiveness and safety outcomes associated with prothrombin complex concentrates.Journal of thrombosis and thrombolysis · 2016Article
- Efficacy of prothrombin complex concentrates for the emergency reversal of dabigatran-induced anticoagulation.Critical care (London, England) · 2016Review
- The European guideline on management of major bleeding and coagulopathy following trauma: fourth edition.Critical care (London, England) · 2016Article
- Guidance for the practical management of warfarin therapy in the treatment of venous thromboembolism.Journal of thrombosis and thrombolysis · 2016Review
- Algorithm for anticoagulation management in geriatric hip fracture patients--Surgeons save Blood.Zeitschrift fur Gerontologie und Geriatrie · 2014Review
- Retrospective Comparison of Andexanet Alfa and 4-Factor Prothrombin Complex for Reversal of Factor Xa-Inhibitor Related Bleeding.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
- Coagulation Factor Xa (Recombinant), Inactivated-Zhzo (Andexanet Alfa) Hemostatic Outcomes and Thrombotic Event Incidence at an Academic Medical Center.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
23935012What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.