Evidence map›Paper›PMID 23934399›Full record

ArticleNanoscale2013

Carbohydrate-actuated nanofluidic diode: switchable current rectification in a nanopipette.

Boaz Vilozny, Alexander L Wollenberg, Paolo Actis, Daniel Hwang, Bakthan Singaram, Nader Pourmand

Abstract read
In one paragraph

Article in Nanoscale, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
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  6. Review
  7. Modulation of Molecular Flux Using a Graphene Nanopore Capacitor.The journal of physical chemistry. B · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Boaz ViloznyDepartment of Biomolecular Engineering, Baskin School of Engineering at University of California Santa Cruz, 1156 High Street, Santa Cruz, CA 95064, USA. pourmand@soe.ucsc.edu.
Alexander L Wollenberg
Paolo Actis
Daniel Hwang
Bakthan Singaram
Nader Pourmand
University of California, Santa Cruz · US

Funding

WHOLE YEAST GENOME TRANSCRIPTIONAL AND FUNCTIONAL GENE MAPS--A FEASIBILITY STUDYP01HG000205 · NHGRI · STANFORD UNIVERSITY · PI HOWE, ROGER THOMAS, JI, HANLEE P · 1990 to 2016
$120.9M
TRANS_NETWORK PROJECTSU54CA143803 · NCI · PRINCETON UNIVERSITY · PI TLSTY, THEA D · 2009 to 2013
$14.2M
A NEW ES CELL DELETION RESOURCE AND WILLIAMS SYNDROMEF32HG000205 · NHGRI · JACKSON LABORATORY · PI GOODWIN, NEAL C · 1999 to 1999
–
NCI NIH HHS U54 CA143803NCI NIH HHS U54CA143803NHGRI NIH HHS F32 HG000205NHGRI NIH HHS P01-35HG000205NHGRI NIH HHS P01 HG000205
6 · The paper itself

Abstract

Nanofluidic structures share many properties with ligand-gated ion channels. However, actuating ion conductance in artificial systems is a challenge. We have designed a system that uses a carbohydrate-responsive polymer to modulate ion conductance in a quartz nanopipette. The cationic polymer, a poly(vinylpyridine) quaternized with benzylboronic acid groups, undergoes a transition from swollen to collapsed upon binding to monosaccharides. As a result, the current rectification in nanopipettes can be reversibly switched depending on the concentration of monosaccharides. Such molecular actuation of nanofluidic conductance may be used in novel sensors and drug delivery systems.

Identifiers

PMID23934399
PMCPMC3827696
OpenAlexW1999214799

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.