ArticleBiological trace element research2013
Tobacco smoke exposure during pregnancy increases maternal blood lead levels affecting neonate birth weight.
Article in Biological trace element research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Post-GWAS gene-environment interplay in breast cancer: results from the Breast and Prostate Cancer Cohort Consortium and a meta-analysis on 79,000 women.Human molecular genetics · 2014Pooled it
- Development and Validation of a Novel Placental DNA Methylation Biomarker of Maternal Smoking during Pregnancy in the ECHO Program.Environmental health perspectives · 2024Trial
- Environmental Lead (Pb) Exposure Versus Fatty Acid Content in Blood and Milk of the Mother and in the Blood of Newborn Children.Biological trace element research · 2016Trial
- Dentine markers of pre/early postnatal lead exposure links with brain, cognitive, and behavioral outcomes in adolescents.medRxiv : the preprint server for health sciences · 2026Article
- Maternal Smoking during Pregnancy, Smoking Initiation, and the Risk of Epilepsy in the UK Biobank.Neuroepidemiology · 2026Article
- Maternal smoking during pregnancy and blood lead levels in US children aged 1-15 years: associations modified by age and race.Paediatrics & child health · 2025Article
- Associations Between the Lead Level in Maternal Blood and Umbilical Cord Blood and Congenital Heart Diseases in Offspring.Biological trace element research · 2023Article
- Article
- Prenatal metal mixture concentrations and reward motivation in children.Neurotoxicology · 2022Article
- Oral exposure to lead for Japanese children and pregnant women, estimated using duplicate food portions and house dust analyses.Environmental health and preventive medicine · 2019Article
- Impact of Perinatal Different Intrauterine Environments on Child Growth and Development: Planning and Baseline Data for a Cohort Study.JMIR research protocols · 2019Article
- Pregnant Inuit Women's Exposure to Metals and Association with Fetal Growth Outcomes: ACCEPT 2010⁻2015.International journal of environmental research and public health · 2019Article
- Determination of lead levels in maternal and umbilical cord blood at birth at the Lagos University Teaching Hospital, Lagos.PloS one · 2019Article
- Maternal Smoking Highly Affects the Function, Membrane Integrity, and Rheological Properties in Fetal Red Blood Cells.Oxidative medicine and cellular longevity · 2019Article
- Monitoring an outdoor smoking area by means of PMEnvironmental science and pollution research international · 2016Article
- Effect of Tocopheryl Acetate on Maternal Cigarette Smoke Exposed Swiss Albino Mice Inbred Fetus.Journal of clinical and diagnostic research : JCDR · 2016Article
- Smoking Behaviors Among Urban and Rural Pregnant Women Enrolled in the Kansas WIC Program.Journal of community health · 2015Article
- Characteristics associated with breastfeeding behaviors among urban versus rural women enrolled in the Kansas WIC program.Maternal and child health journal · 2015Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To assess the effect of lead exposure from cigarette smoke on fetal growth, blood lead concentrations were measured using inductively coupled plasma mass spectrometry in 150 healthy pregnant women. Mean lead concentrations in plasma and whole blood were significantly higher in the smoking group compared with the nonsmoking group in each trimester of pregnancy (p < 0.001). Logistic regression analysis showed the highest impact of the number of cigarettes smoked per day for serum lead concentration (β = 0.238; p < 0.05), while in whole blood, it was duration of smoking before conception (β = 0.297; p < 0.001). Birth weight of the smoking mothers' infants was significantly lower (mean ± SEM, 3,192 ± 50.8 and 3,569 ± 49.6 g, respectively; p < 0.001) and negatively correlated with lead levels in plasma (r = -0.38; p < 0.001) and in whole blood (r = -0.27; p < 0.001). Therefore, it is suggested that smoking during pregnancy increases lead concentrations in maternal blood. Fetal exposure to low doses of lead in utero may be a serious risk factor causing lower birth weight.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.