Evidence map›Paper›PMID 23933967›Full record

ArticleJournal of biomedical optics2013

Multispectral imaging in the extended near-infrared window based on endogenous chromophores.

Qian Cao, Natalia G Zhegalova, Steven T Wang, Walter J Akers, Mikhail Y Berezin

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Optoacoustic muscle imaging.Journal of neuromuscular diseases · 2026
    Review
  2. Article
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  6. Review
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  10. Detection of Shortwave-Infrared Cerenkov Luminescence from Medical Isotopes.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  11. Review
  12. Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qian CaoWashington University School of Medicine, Department of Radiology, St. Louis, Missouri 63110, USA.
Natalia G Zhegalova
Steven T Wang
Walter J Akers
Mikhail Y Berezin

Funding

DEVELOPMENT OF OPTICAL NANOTHERMOMETERS FOR MEDICAL APPLICATIONSR21CA149814 · NCI · WASHINGTON UNIVERSITY · PI BEREZIN, MIKHAIL Y. · 2010 to 2011
$353k
NCI NIH HHS R21 CA149814NCI NIH HHS R21CA149814NHLBI NIH HHS HHSN268201000046C
6 · The paper itself

Abstract

To minimize the problem with scattering in deep tissues while increasing the penetration depth, we explored the feasibility of imaging in the relatively unexplored extended near infrared (exNIR) spectral region at 900 to 1400 nm with endogenous chromophores. This region, also known as the second NIR window, is weakly dominated by absorption from water and lipids and is free from other endogenous chromophores with virtually no autofluorescence. To demonstrate the applicability of the exNIR for bioimaging, we analyzed the optical properties of individual components and biological tissues using an InGaAs spectrophotometer and a multispectral InGaAs scanning imager featuring transmission geometry. Based on the differences in spectral properties of tissues, we utilized ratiometric approaches to extract spectral characteristics from the acquired three-dimensional "datacube". The obtained images of an exNIR transmission through a mouse head revealed sufficient details consistent with anatomical structures.

Indexed as

AnimalsFemaleHeadImage Processing, Computer-AssistedLipidsMiceMice, NudeModels, BiologicalOptical ImagingSpectroscopy, Near-InfraredWaterLipidsWater

Identifiers

PMID23933967
PMCPMC3739874

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.